Principles of Anatomy and Physiology
Principles of Anatomy and Physiology
15th Edition
ISBN: 9781119329398
Author: Gerard J Tortora, Bryan Derrickson
Publisher: John Wiley & Sons Inc
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Chapter 21, Problem 11CP
Summary Introduction

To review:

The transportation of the impure blood to the heart from the body via veins.

Introduction:

The blood that has passed through the capillaries of various tissues other than the lungs and which is now deoxygenated is found in the veins. This blood is called the venous blood. This deoxygenated blood needs to go back to the heart, which directs the impure blood to the lungs for its purification. This process of return of blood from different body parts via the heart to the lungs is termed as a venous return.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
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