Chapter 20.10, Problem 6LTS

Interpretation Introduction

Interpretation:

To accomplish the target products transformation should be draw and identified, using a selective reagent.

Concept introduction:

Nucleophilic reaction: electron rich nucleophiles attack the positive or partially positive charge of an atom and replace a leaving group is called Nucleophilic Substitution reaction.

$S_{N}1$Reaction: The $S_{N}1$ reaction is twostep process, leaving group leaves the molecule is first step and forms the more stable carbocation. Further, nucleophile attacks the carbocation and forms the final product in the second step. The rate of the reaction depends on the stability of the carbocation.

$S_{N}2$Reaction: The $S_{N}2$ reaction is single step process, leaving group leaves the molecule and nucleophiles attack the molecule is single step process which is simultaneous process.

Wittig reaction: This process allows the preparation of an alkene by the reaction of an aldehyde ( $\text{-CHO}$) or ketone ( $\text{-C=O}$) with ylides generated from a phosphonium salt. The geometry of the resulting cis, trans alkene depends on the reactivity of the ylide.

To identify: The synthetic route to accomplish the given transformation.