a. To determine: The frequency of allele responsible for alkaptonuri. Introduction: Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

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Answer 1

Question

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

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Answer 2

Question

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

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Answer 3

Question

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

Expert Solution & Answer

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Answer 4

Question

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

Expert Solution & Answer

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Answer 5

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

Answer 6

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Answer 7

Chapter 20, Problem 9P

Summary Introduction

a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Answer 8

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Answer 9

Summary Introduction

b.

To determine:

The proportion of the population of U.S. that is carrier of alkaptonuria. The ratio of carriers of alkaptonuria to individuals affected by alkaptonuria.

Introduction:

The individuals that carry disease-causing genes are called carriers. The carriers are not the sufferer. The role of carriers is to pass the disease-causing genes to the next generation. Alkaptonuria is also a genetic disorder that is transmitted by the carriers to the next generation offsprings.

Answer 10

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Answer 11

Summary Introduction

c.

To determine:

The chance that a child produced by the woman from her second marriage would have alkaptonuria.

Introduction:

The woman produces a child suffering from alkaptonuria from the first marriage. After some time, the woman gets remarried to another to another man. The woman can produce normal as well as the abnormal child with her second husband.

Answer 12

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

Answer 13

Summary Introduction

d.

To determine:

Whether the assumption of Hardy-Weinberg equilibrium can be used to estimate the allele frequencies and carrier frequencies of severe recessive autosomal disorders.

Introduction:

Geoffrey H. Hardy was a scientist who proposed the concept of Hardy-Weinberg equilibrium. This concept is used to associate the allele frequency with the genotype frequency. The proportion of gene copies that are of a common allele type in a population is termed as allele frequency.

Answer 14

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Answer 15

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Answer 16

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Answer 17

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a. To determine: The frequency of allele responsible for alkaptonuri. Introduction: Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

Solution Summary: The author explains that the Hardy-Weinberg equilibrium is used to associate the phenotype frequency with the genotype frequency.

Concept explainers

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a.

To determine:

The frequency of allele responsible for alkaptonuri.

Introduction:

Alkaptonuria is a type of disorder. It is a recessive autosomal genetic disorder. It is related to the darkening of urine. It has been found that 1 out of every 250,000 people suffer from this disorder.

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Chapter 20 Solutions