Genetics: From Genes to Genomes, 5th edition
Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 20, Problem 17P

Androgenetic alopecia (pattern baldness) is a complex trait in humans governed by several genes, but suppose a human population exists in which a single autosomal allele determines pattern baldness. This allele is dominant in males and recessive in females. The population is in Hardy-Weinberg equilibrium, and 51% of the men are bald.

a. What is the allele frequency of the baldness allele among males?
b. What is the allele frequency of the baldness allele among females?
c. What percentage of the women in this population will exhibit pattern baldness?
d. Assuming random mating, what proportion of all matings should be between a bald man and a nonbald woman?
e. What percentage of the bald men in the population are heterozygotes?
f. If a nonbald couple produces a bald son, what is the probability that their next son will be bald?
g. A woman with androgenetic alopecia has a daughter, but nothing is known about the father. What is the probability that the daughter will be bald?
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Genetics: From Genes to Genomes, 5th edition

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