The necessity to break the total serum cholesterol level into an LDL and HDL component. Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

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Answer 1

Question

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

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The beta-lactamase hydrolyzes the lactam-ring in penicillin. Describe the mechanism of hydrolysis, insuring to include the involvement of S, D, & K in the reaction sequence. Please help

To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?

To map the active site of -lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Using the experimental results described above derive the primary sequence of the active site hexapeptide. Please help!

Answer 2

Question

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

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Check out a sample textbook solution

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Answer 3

Question

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Expert Solution & Answer

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Check out a sample textbook solution

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Answer 4

Question

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 6

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 7

Chapter 20, Problem 1MTE

Summary Introduction

To explain: The necessity to break the total serum cholesterol level into an LDL and HDL component.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 8

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 9

Summary Introduction

To determine: The levels of LDL cholesterol and HDL cholesterol that are considered as normal.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 10

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 11

Summary Introduction

To determine: The level of HDL cholesterol and LDL cholesterol that are associated with an increased risk of cardiovascular disease.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 12

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 13

Summary Introduction

To determine: The type of drugs other than statins, affects the serum cholesterol levels.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 14

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 15

Summary Introduction

To explain: The action of the drug against the cholesterol and the reason why they are used in combination.

Concept introduction: Cholesterol is a fatty substance required by our body to make hormones, vitamin D, and bile acids to aid the digestion. It is also needed to build and maintain the cell’s outer wall. It cannot dissolve in the blood and therefore, it is carried around by proteins. These fat and protein complexes are called lipoproteins.

Answer 16

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Answer 17

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Answer 19

Ch. 20 - Prob. 1E Ch. 20 - 2. Identify die products generated by the action...Ch. 20 - 3. (a) What is. the charge of bile acids in the...Ch. 20 - 4. Bacteria that live in the large intestine...Ch. 20 - Prob. 5E Ch. 20 - 6. Adipocytes store fat in phospholipid-coaled...Ch. 20 - Prob. 7E Ch. 20 - Prob. 8E Ch. 20 - 9. The first three steps of ? oxidation (Fig....Ch. 20 - Prob. 10E

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