Bisphenol A is widely used as a building block in polymer synthesis and found in the polycarbonate hard plastics of reusable drink containers, DVD, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative. Concept Introduction: BFA is harmful and can cause systemic damage to the human body. BPA is present in food or beverages containers, where it leaches into the food. BPA causes myriad of health problems such as it affects the brain development, prostate gland of fetuses, infants and children. BPA has been linked to high blood pressure.

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 20, Problem 13P

Interpretation Introduction

Interpretation:

Bisphenol A is widely used as a building block in polymer synthesis and found in the polycarbonate hard plastics of reusable drink containers, DVD, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative.

Concept Introduction:

BFA is harmful and can cause systemic damage to the human body. BPA is present in food or beverages containers, where it leaches into the food. BPA causes myriad of health problems such as it affects the brain development, prostate gland of fetuses, infants and children. BPA has been linked to high blood pressure.

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The beta-lactamase hydrolyzes the lactam-ring in penicillin. Describe the mechanism of hydrolysis, insuring to include the involvement of S, D, & K in the reaction sequence. Please help

To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?

To map the active site of -lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Using the experimental results described above derive the primary sequence of the active site hexapeptide. Please help!

Answer 2

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Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 20, Problem 13P

Interpretation Introduction

Interpretation:

Bisphenol A is widely used as a building block in polymer synthesis and found in the polycarbonate hard plastics of reusable drink containers, DVD, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative.

Concept Introduction:

BFA is harmful and can cause systemic damage to the human body. BPA is present in food or beverages containers, where it leaches into the food. BPA causes myriad of health problems such as it affects the brain development, prostate gland of fetuses, infants and children. BPA has been linked to high blood pressure.

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Answer 3

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 20, Problem 13P

Interpretation Introduction

Interpretation:

Bisphenol A is widely used as a building block in polymer synthesis and found in the polycarbonate hard plastics of reusable drink containers, DVD, cell phones, and other consumer goods. Bisphenol A is reported to have estrogenic activity, and its widespread occurrence in our environment is a potential concern. Describe one or two biochemical experiments that could be done to compare the activity of bisphenol A with that of its estradiol, its structural relative.

Concept Introduction:

BFA is harmful and can cause systemic damage to the human body. BPA is present in food or beverages containers, where it leaches into the food. BPA causes myriad of health problems such as it affects the brain development, prostate gland of fetuses, infants and children. BPA has been linked to high blood pressure.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Chemical process in which one or more monomers combine to produce a very large chain-like molecule called a polymer. The functional groups present on the monomers and their steric effects are responsible for polymerization through a sequence of reactions that vary in complexity. There exists a stable covalent chemical bond between monomers that sets apart polymerization from other processes.

Chapter 20, Problem 13P

Interpretation Introduction