Introduction to Genetic Analysis
Introduction to Genetic Analysis
11th Edition
ISBN: 9781464109485
Author: Anthony J.F. Griffiths, Susan R. Wessler, Sean B. Carroll, John Doebley
Publisher: W. H. Freeman
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Chapter 2, Problem 64P

a.

Summary Introduction

To determine: The probability that the child will have cystic fibrosis.

Introduction: Cystic fibrosis is a genetic disease often affecting the lungs and also the pancreas, liver, kidneys, and intestine. The long-term effects involve difficulty in breathing and coughing up mucus as a consequence of repeated lung infections.

b.

Summary Introduction

To determine: The chance that the children will have the precise Mendelian ratio of 3:1 for normal cystic fibrosis.

Introduction: The Mendelian ratio exists of several phenotypes in a cross concerning Mendelian characters, especially with the ratio 3:1 prepared by the second filial generation of offspring from parents contrasting concerning a single character.

c.

Summary Introduction

To determine: The probability that their next three children will be normal, if their first child has cystic fibrosis.

Introduction: Cystic fibrosis is a continuous genetic disorder that induces persistent infections in the lung and restricts the strength to breathe over time. In people with CF, mutations within the transmembrane of cystic fibrosis conductance regulator gene cause the CFTR protein to become dysfunctional.

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Introduction to Genetic Analysis

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