a.
To determine: The way by which disorder inherited with well-defined reasons.
Introduction: The genetic abnormalities which are transmitted from parents to the offsprings and then to their grandsons or granddaughters are referred to as the genetic disorders. Genetic diseases may be of two main types, the sex chromosomal and the autosomal derived diseases.
b.
To determine: The genotypes for many individuals in the given pedigree as possible.
Introduction: Dominant abnormalities are those who express their defects in their progenies dominantly. However, the recessive abnormalities can skip the generations as a healthy dominant gene can suppress the behavior of the recessive character.
c.
To determine: The expected proportion containing all unaffected children from the four unaffected children of parents III-4 and III-5.
Introduction: From the pedigree, if a cross is made between the affected and non-affected parents, the progenies produced as a result of the cross will be of both types, the dominant as well as the recessive type. Recessive progenies will be healthy that do not carry the abnormal genes. However, the dominant progenies will carry the diseased genes.
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Introduction to Genetic Analysis
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