The probability of an affected child, if mother’s brother is affected. Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

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Answer 1

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 2

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 3

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Expert Solution & Answer

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Answer 4

Question

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

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Answer 5

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 6

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

Answer 7

Chapter 2, Problem 61P

a.

Summary Introduction

To determine: The probability of an affected child, if mother’s brother is affected.

Introduction : Duchenne muscular dystrophy is a critical type of muscular dystrophy. The sign of muscle defect begins typically around the age of four in boys and worsens quickly. Usually, muscle loss happens earliest in the thighs and pelvis, accompanied by the arms.

Answer 8

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Answer 9

b.

Summary Introduction

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Answer 10

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 11

c.

Summary Introduction

To determine: The probability that an individual’s have received the allele, if the father’s brother had the disease.

Introduction: DMD happens due to the mutated DMD gene fails to compose some functional dystrophin mostly. Individuals with BMD genetic mutations produce dystrophin that is partly functional and preserves their muscles from deteriorating as severely or as promptly as in DMD.

Answer 12

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Answer 13

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Answer 14

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Answer 15

Ch. 2 - Prob. 1P Ch. 2 - Prob. 2P Ch. 2 - Prob. 3P Ch. 2 - Prob. 4P Ch. 2 - Prob. 6P Ch. 2 - Prob. 7P Ch. 2 - Prob. 8P Ch. 2 - Prob. 9P Ch. 2 - Prob. 10P Ch. 2 - Prob. 11P

Solution Summary: The author explains that Duchenne muscular dystrophy is acquired in an X-linked pattern because of the gene that can conduct a DMD-causing mutation on the Y chromosome.

Concept explainers

Videos

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Want to see the full answer?

Chapter 2 Solutions

Solution Summary: The author explains that Duchenne muscular dystrophy is acquired in an X-linked pattern because of the gene that can conduct a DMD-causing mutation on the Y chromosome.

Concept explainers

Videos

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease. Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.

Want to see the full answer?

Chapter 2 Solutions

To determine: The probability that offspring have received the allele, if an individual’s mother's brother had Duchenne's disease.

Introduction: A gene defect causes the disease or mutation induces the gene helping the body to compose a protein termed dystrophin.