To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin. Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

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Answer 1

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Amino Acid Coclow TABle 3' Gly Phe Leu (G) (F) (L) 3- Val (V) Arg (R) Ser (S) Ala (A) Lys (K) CAG G Glu Asp (E) (D) Ser (S) CCCAGUCAGUCAGUCAG 0204 C U A G C Asn (N) G 4 A AGU C GU (5) AC C UGA A G5 C CUGACUGACUGACUGAC Thr (T) Met (M) lle £€ (1) U 4 G Tyr Σε (Y) U Cys (C) C A G Trp (W) 3' U C A Leu בוט His Pro (P) ££ (H) Gin (Q) Arg 흐름 (R) (L) Start Stop 8. Transcription and Translation Practice: (Video 10-1 and 10-2) A. Below is the sense strand of a DNA gene. Using the sense strand, create the antisense DNA strand and label the 5' and 3' ends. B. Use the antisense strand that you create in part A as a template to create the mRNA transcript of the gene and label the 5' and 3' ends. C. Translate the mRNA you produced in part B into the polypeptide sequence making sure to follow all the rules of translation. 5'-AGCATGACTAATAGTTGTTGAGCTGTC-3' (sense strand) 4

Answer 2

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Answer 3

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Expert Solution & Answer

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Answer 4

Question

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

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Answer 5

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 6

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Answer 7

Chapter 2, Problem 52P

a.

Summary Introduction

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Answer 8

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 9

b.

Summary Introduction

To find: The probability that the first child of cousin will be diseased (from Tay-Sachs abnormality) by assuming the outsider to be homozygous and normal.

Introduction: The genetic abnormality caused due to the accumulation of the toxic substances in the body due to the gene mutation caused by Tay-Sachs disease. The symptoms of the disease lead to destroying the brain and spinal cord. The disease becomes apparent at the infancy stage.

Answer 10

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Answer 11

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Answer 12

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Answer 13

Ch. 2 - Prob. 1P Ch. 2 - Prob. 2P Ch. 2 - Prob. 3P Ch. 2 - Prob. 4P Ch. 2 - Prob. 6P Ch. 2 - Prob. 7P Ch. 2 - Prob. 8P Ch. 2 - Prob. 9P Ch. 2 - Prob. 10P Ch. 2 - Prob. 11P

To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin. Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

Solution Summary: The author explains that the disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews.

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To draw: The pedigree showing all possible outcomes resulted from the cross between a woman with her first male cousin.

Introduction: The disease Tay-Sachs occurs due to the recessive allele, which is common in Eastern European Ashkenazi Jews and rarer in other regions.

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Chapter 2 Solutions