Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 2, Problem 4CAE
The antibiotic amphotericin B causes leaks in cells by combining with sterols in the plasma membrane. Would you expect to use amphotericin B against a bacterial infection? A fungal infection? Offer a reason why amphotericin B has severe side effects in humans.
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Amoeboid cells that migrate through our tissues, such as the class of white blood cells known as neutrophils, often do so in a directed manner, triggered, for instance, by chemical signals released by pathogens such as bacteria. Directed migration in response to a chemical stimulus is known as chemotaxis. Part of an efficient chemotactic response is the ability of cells to polarize. As is the case with our structurally-polar polymers like F-actin or microtubules, polarization here refers to an asymmetry in the cells, rather than an electrical charge. In this case, it involves one part of the cell becoming the “front” (or leading edge) and another the rear. In a well-polarized, migrating cell, it’s been observed that an active form of Rac (which, in turn, can activate ARP 2/3) is concentrated towards the front of the cell, whereas an active form of Rho (which, in turn, can activate formin, inhibit cofilin/ADP, and activate myosin II) is found toward the rear of the cell. Based on your…
Amoeboid cells that migrate through our tissues, such as the class of white blood cells known as neutrophils, often do so in a directed manner, triggered, for instance, by chemical signals released by pathogens such as bacteria. Directed migration in response to a chemical stimulus is known as chemotaxis. Part of an efficient chemotactic response is the ability of cells to polarize. As is the case with our structurally-polar polymers like F-actin or microtubules, polarization here refers to an asymmetry in the cells, rather than an electrical charge. In this case, it involves one part of the cell becoming the “front” (or leading edge) and another the rear. In a well-polarized, migrating cell, it’s been observed that an active form of Rac (which, in turn, can activate ARP 2/3) is concentrated towards the front of the cell, whereas an active form of Rho (which, in turn, can activate formin, inhibit ADP, and activate myosin II) is found toward the rear of the cell. Based on your…
The antibiotic amphotericin B causes leaks in cells by combining with sterols in the
plasma membrane. Would you expect to use amphotericin B against a bacterial
infection? Would it work against a fungal infection? Justify both of your answers.
Chapter 2 Solutions
Microbiology: An Introduction
Ch. 2 - What is a chemical element?Ch. 2 - DRAW IT Diagram the electronic configuration of a...Ch. 2 - What type of bond holds the following atoms...Ch. 2 - Classify the following types of chemical...Ch. 2 - Bacteria use the enzyme urease to obtain nitrogen...Ch. 2 - Classify the following as subunits of either a...Ch. 2 - DRAW IT The artificial sweetener aspartame, or...Ch. 2 - DRAW IT The following diagram shows the...Ch. 2 - Prob. 9RCh. 2 - Prob. 10R
Ch. 2 - Assume E. coli bacteria are grown in a nutrient...Ch. 2 - If Pseudomonas bacteria are supplied with...Ch. 2 - If E. coli were grown in a medium containing the...Ch. 2 - Prob. 4MCQCh. 2 - Prob. 5MCQCh. 2 - Prob. 6MCQCh. 2 - The dissociation products of the molecules are...Ch. 2 - Prob. 8MCQCh. 2 - The dissociation products of the molecules are...Ch. 2 - Prob. 10MCQCh. 2 - When you blow bubbles into a glass of water, the...Ch. 2 - Prob. 2ACh. 2 - Prob. 3ACh. 2 - Prob. 4ACh. 2 - Prob. 1CAECh. 2 - Prob. 2CAECh. 2 - Newborn babies are tested for phenylketonuria...Ch. 2 - The antibiotic amphotericin B causes leaks in...Ch. 2 - Prob. 5CAE
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