EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI
EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI
12th Edition
ISBN: 8220103633604
Author: KELLER
Publisher: PEARSON
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Chapter 2, Problem 43CT

Sarah is quite proud of her slender, model-like figure and boasts that she doesn't have an “ounce of excess body fat.” Lauren, in contrast, is grossly overweight. She complains of feeling hot most of the time, and on a hot day she is miserable, Sarah generally feels chilled except on very hot days. Explain the relative sensitivity to environmental temperature of these two women on the basis of information you have been given in the Organic Compounds section of this chapter.

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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.  b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake? Options: A. Dose; Increase dose     B. Dose; Decrease dose     C. Dose; Do not change dose     D. Interval; Increase the interval between doses (give the drug less frequently)    E. Interval; Decrease the interval between doses (give the drug more frequently)     F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math

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EBK ESSENTIALS OF HUMAN ANATOMY & PHYSI

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