General, Organic, and Biological Chemistry: Structures of Life (5th Edition)
General, Organic, and Biological Chemistry: Structures of Life (5th Edition)
5th Edition
ISBN: 9780321967466
Author: Karen C. Timberlake
Publisher: PEARSON
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Chapter 19.6, Problem 19.43QAP

What dipeptides could be produced from the partial hydrolysis of His-Met-Gly-Val?

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need help please and thanks dont understand a-b Learning Goal: As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT. The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7).   Part A - Difference in binding free eenergies Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol. The margin of error is 2%.   Part B - Compare difference in free energy to the thermal energy Divide the…
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Chapter 19 Solutions

General, Organic, and Biological Chemistry: Structures of Life (5th Edition)

Ch. 19.1 - Prob. 19.11QAPCh. 19.1 - Prob. 19.12QAPCh. 19.2 - Prob. 19.13QAPCh. 19.2 - Draw the zwitterion for each of the following...Ch. 19.2 - Prob. 19.15QAPCh. 19.2 - Draw the zwitterion for each of the following...Ch. 19.2 - Prob. 19.17QAPCh. 19.2 - Prob. 19.18QAPCh. 19.3 - Draw the structure for each of the following...Ch. 19.3 - Draw the structure for each of the following...Ch. 19.3 - Prob. 19.21QAPCh. 19.3 - Prob. 19.22QAPCh. 19.3 - Prob. 19.23QAPCh. 19.3 - Peptides from sweet potato with antioxidant...Ch. 19.4 - Prob. 19.25QAPCh. 19.4 - Prob. 19.26QAPCh. 19.4 - Prob. 19.27QAPCh. 19.4 - Prob. 19.28QAPCh. 19.4 - Prob. 19.29QAPCh. 19.4 - Prob. 19.30QAPCh. 19.4 - Prob. 19.31QAPCh. 19.4 - Prob. 19.32QAPCh. 19.4 - Prob. 19.33QAPCh. 19.4 - Prob. 19.34QAPCh. 19.5 - Prob. 19.35QAPCh. 19.5 - Prob. 19.36QAPCh. 19.5 - Prob. 19.37QAPCh. 19.5 - Prob. 19.38QAPCh. 19.5 - Prob. 19.39QAPCh. 19.5 - Prob. 19.40QAPCh. 19.6 - What products would result from the complete...Ch. 19.6 - Prob. 19.42QAPCh. 19.6 - What dipeptides could be produced from the partial...Ch. 19.6 - Prob. 19.44QAPCh. 19.6 - What structural level of a protein is affected by...Ch. 19.6 - Prob. 19.46QAPCh. 19.6 - Prob. 19.47QAPCh. 19.6 - Indicate the changes in the secondary and tertiary...Ch. 19.6 - Prob. 19.49QAPCh. 19.6 - Prob. 19.50QAPCh. 19.6 - 19.51 What is the difference between the secondary...Ch. 19.6 - Prob. 19.52QAPCh. 19.6 - Prob. 19.53QAPCh. 19.6 - Prob. 19.54QAPCh. 19 - Prob. 19.55UTCCh. 19 - Prob. 19.56UTCCh. 19 - Prob. 19.57UTCCh. 19 - Prob. 19.58UTCCh. 19 - Prob. 19.59UTCCh. 19 - Each of three peptides contains one glycine...Ch. 19 - Prob. 19.61UTCCh. 19 - Prob. 19.62UTCCh. 19 - Prob. 19.63AQAPCh. 19 - Prob. 19.64AQAPCh. 19 - Prob. 19.65AQAPCh. 19 - Prob. 19.66AQAPCh. 19 - Prob. 19.67AQAPCh. 19 - Prob. 19.68AQAPCh. 19 - Wou4d you expect a polypeptide with a high content...Ch. 19 - Prob. 19.70AQAPCh. 19 - Prob. 19.71AQAPCh. 19 - Prob. 19.72AQAPCh. 19 - Prob. 19.73AQAPCh. 19 - Prob. 19.74AQAPCh. 19 - Prob. 19.75AQAPCh. 19 - Prob. 19.76AQAPCh. 19 - Prob. 19.77AQAPCh. 19 - Prob. 19.78AQAPCh. 19 - Indicate the overall charge of each amino acid at...Ch. 19 - Prob. 19.80CQCh. 19 - Prob. 19.81CQCh. 19 - Prob. 19.82CQ
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