Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 19, Problem 6P
Interpretation Introduction
Interpretation:
Leukemia is a neoplastic (cancerous) proliferation of white blood cells. Clinicians are currently testing deoxycoformycin, an adenosine deaminase inhibitor, as a possible antileukemic agent. The reason this therapy is effective.
Concept Introduction:
2'-deoxycoformycin (dCF) is an inhibitor of adenosine deaminase. dCF targets leukemia, myeloid, erythroid and lymphoma cells for apoptosis in the presence of either 2'-deoxyadenosine (dAdo) or its analog adenine arabinoside (araA).
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Biochemistry: Concepts and Connections (2nd Edition)
Ch. 19 - Prob. 1PCh. 19 - Prob. 2PCh. 19 - Predict the effects of the following compounds on...Ch. 19 - Prob. 4PCh. 19 - Prob. 5PCh. 19 - Prob. 6PCh. 19 - Prob. 7PCh. 19 - A classic way to isolate thymidylate...Ch. 19 - Prob. 9PCh. 19 - Prob. 10P
Ch. 19 - Prob. 11PCh. 19 - Prob. 12PCh. 19 - Prob. 13PCh. 19 - Prob. 14PCh. 19 - Prob. 15PCh. 19 - Prob. 16PCh. 19 - Prob. 17PCh. 19 - Prob. 18PCh. 19 - Prob. 19PCh. 19 - Prob. 20PCh. 19 - Prob. 21PCh. 19 - Prob. 22PCh. 19 - Prob. 23PCh. 19 - Prob. 24PCh. 19 - Prob. 25PCh. 19 - Prob. 26PCh. 19 - Prob. 27P
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