Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
Question
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Chapter 19, Problem 11P
Interpretation Introduction

(a) Interpretation:

Which intermediates in the purine nucleotide synthesis would accumulate in DON treated cells.

Introduction:

The 6-diazo-5-oxonorleucine is nonstandard amino acids. It is a glutamine antagonist and acts as a glutamine dependant amidotransferase.

Interpretation Introduction

(b) Interpretation:

Which intermediates in the pyrimidine nucleotide synthesis would accumulate in DON treated cells.

Introduction:

The 6-diazo-5-oxonorleucine is nonstandard amino acids. It is a glutamine antagonist and acts as a glutamine dependant amidotransferase.

Interpretation Introduction

(c) Interpretation:

Mechanism of the inhibition of the enzymes by DON.

Introduction:

The 6-diazo-5-oxonorleucine (DON) is nonstandard amino acids. It is a glutamine antagonist and acts as a glutamine dependant amidotransferase.

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