Microbiology: A Systems Approach
Microbiology: A Systems Approach
4th Edition
ISBN: 9780073402437
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 19, Problem 5MCQ
Summary Introduction

Introduction:

Chronic form of meningitis is caused by Cryptococcus neoformans. The symptoms arise gradually. The most common symptom is headache; however, neck stiffness and nausea are other symptoms.

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a) The lux operon is under positive control. Based on this information, does the luxR regulator sequence make a repressor protein or an activator protein? b) How will binding of this complex affect RNA polymerase? Remember this operon is under positive control. c) AHL is a signal molecule that V. fisheri makes to communicate with neighboring bacterial cells. This molecule can diffuse outside of the cell and into another bacterial cell in close proximity. This type of communication between bacterial cells is known as quorum sensing. If bacterial cell density is low how will this affect the lux operon? What will happen if the density is high?
1) Given an mRNA with the following sequence, please translate the codons to a chain of amino acids. Use the codon chart below.5’AUG/CCU/GCU/UAC/CGG/GAG/UAA3’ “met-_________-_________-_________-_________-_________”STOP”   2) Assuming the original polypeptide chain below, match each type of point mutation with the polypeptide chain that results.   Original polypeptide: Pro-Thr-Ser-Leu-Leu-His-Asn A.    Missense B.    Silent C.     Nonsense D.    Frameshift   ______ Pro-Thr-Ser-STOP     ______ Pro-Thr-Ser-Leu-Ile-His-Asn     ______ Pro-Thr-Ser-Leu-Leu-His-Asn     _______ Pro-Thr-His-Cys-Tyr-Thr
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