For the given reaction, the missing intermediate and reagents are to be determined. Concept introduction: MCPBA is an oxidant that converts an alkene to an epoxide . Grignard reagent is used to open the epoxide rings under basic conditions by using S N 2 mechanism. The tert-butyldimethylsilyl chloride (TBDMS-Cl) is the silyl ether protecting agent in the multistep organic synthesis . Tetra-n-butyl ammonium fluoride (TBAF) i.e. Bu 4 NF is used to remove silyl ether protecting groups.

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Chapter 19, Problem 19.67P

Interpretation Introduction

Interpretation:

For the given reaction, the missing intermediate and reagents are to be determined.

Concept introduction:

MCPBA is an oxidant that converts an alkene to an epoxide. Grignard reagent is used to open the epoxide rings under basic conditions by using SN2 mechanism. The tert-butyldimethylsilyl chloride (TBDMS-Cl) is the silyl ether protecting agent in the multistep organic synthesis. Tetra-n-butyl ammonium fluoride (TBAF) i.e. Bu4NF is used to remove silyl ether protecting groups.

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