Chapter 19, Problem 19.11P

Interpretation Introduction

Interpretation:

A way to carry out the given synthesis is to be proposed.

Concept introduction:

A synthesis may be designed by thinking in the reverse direction, from the product to the starting compound, in a method called retrosynthesis. Retrosynthesis involves starting with the product and determining a suitable precursor from which it can be synthesized, without considering specific reactions. This synthesis is carried out by retro of Wolf-Kishner reduction. The Wolff–Kishner reduction converts the carbonyl ($\text{C = O}$) group of a ketone or aldehyde into a ${\text{CH}}_{\text{2}}$ group. Thus, a Wolff–Kishner reaction removes the $\text{C = O}$ functional group of a ketone or aldehyde.