How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown. Concept introduction: Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde . To show: How to prepare o-hydroxyphenylacetaldehyde from phenol.

Question

> You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: 1. ☑ CI 2. H3O+ O Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. Explanation Check ? DO 18 Ar B © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

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> You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: 1. ☑ CI 2. H3O+ O Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. Explanation Check ? DO 18 Ar B © 2025 McGraw Hill LLC. All Rights Reserved. Terms of Use | Privacy Center | Accessibility

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Consider a solution of 0.00304 moles of 4-nitrobenzoic acid (pKa = 3.442) dissolved in 25 mL water and titrated with 0.0991 M NaOH. Calculate the pH at the equivalence point

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction