How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown. Concept introduction: Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde . To show: How to prepare o-hydroxyphenylacetaldehyde from phenol.

Question

Blocking Group are use to put 2 large sterically repulsive group ortho. Show the correct sequence toconnect the reagent to product with the highest yield possible. * see image **NOTE: The compound on the left is the starting point, and the compound on the right is the final product. Please show the steps in between to get from start to final, please. These are not two different compounds that need to be worked.

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

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See solution

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Blocking Group are use to put 2 large sterically repulsive group ortho. Show the correct sequence toconnect the reagent to product with the highest yield possible. * see image **NOTE: The compound on the left is the starting point, and the compound on the right is the final product. Please show the steps in between to get from start to final, please. These are not two different compounds that need to be worked.

I dont understand this.

Can you please explain this prooblem to me, show me how the conjugation is added, did I add them in the correct places and if so please show me. Thanks!

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction

Interpretation:

How to prepare o-hydroxyphenylacetaldehyde from phenol is to be shown.

Concept introduction:

Phenyl acetaldehyde is to be prepared from phenol. Phenol can be converted into o-ethylphenol by Friedal Crafts reaction. The benzyl carbon can be brominated by treating with NBS. The dehydrohalogeation of the bromo compound and subsequent treatment with peracid will lead to the formation of an epoxide in the side chain. Upon acidification the epoxide ring gets opened to yield an enol which will tautomerize to an aldehyde.

To show:

How to prepare o-hydroxyphenylacetaldehyde from phenol.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C=O, as their functional group. The carbonyl group in aldehydes is placed at the end of the molecular structure, which means the C=O is attached to one hydrogen atom and an alkyl group or a benzene ring. Just like all the other homologous series in organic chemistry, the naming of aldehydes uses the suffix “-al”. The general molecular formula is C n H 2n O.

Chapter 18.SE, Problem 65GP

Interpretation Introduction