Chapter 18.SE, Problem 35MP

Interpretation Introduction

Interpretation:

Given that acifluorfen can be prepared by a route that begins with reaction between a phenol and aryl fluoride. A mechanism for the reaction is to be proposed.

Concept introduction:

The reaction between the phenoxide ion and the aryl fluoride is an aromatic nucleophilic substitution reaction which takes place through the formation of a Meisenheimer complex. The phenol can be converted into a phenoxide ion by treatment with a base.

To propose:

A mechanism for the formation of acifluorfen by a route that begins with reaction between a phenol and aryl fluoride.