The best reaction sequence that accomplishes the given transformation has to be determined from the given sequences. Concept Introduction: Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors. Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho–para directing. Halogens are deactivators that are ortho–para directing. Friedel-Crafts Acylation: This Lewis acid-catalyzed electrophilic aromatic substitution is the reaction between arenes and acyl chlorides or anhydrides for the synthesis of monoacylated compound. The products are deactivated, as well as do not undergo a second substitution. Bromination: In bromination reaction, hydrogen atom of a molecule is replaced by a bromine atom. Reduction: If electrons are gained to a species or hydrogen atoms are added to a species or oxygen atom gets removed from a species during a chemical reaction is known as reduction.

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Chapter 18, Problem 90IP

Interpretation Introduction

Interpretation:

The best reaction sequence that accomplishes the given transformation has to be determined from the given sequences.

Concept Introduction:

Deactivators are electron withdrawing groups attached to the benzenes that have either positive charge or an atom with high electronegativity. They are meta directors.

Activators are electron donating groups attached to the benzenes that have either electron density that is able to push into benzene ring or a lone pair of electrons. They are ortho–para directing.

Halogens are deactivators that are ortho–para directing.

Friedel-Crafts Acylation: This Lewis acid-catalyzed electrophilic aromatic substitution is the reaction between arenes and acyl chlorides or anhydrides for the synthesis of monoacylated compound. The products are deactivated, as well as do not undergo a second substitution.

Bromination: In bromination reaction, hydrogen atom of a molecule is replaced by a bromine atom.

Reduction: If electrons are gained to a species or hydrogen atoms are added to a species or oxygen atom gets removed from a species during a chemical reaction is known as reduction.

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