Chapter 18, Problem 7CONQ

Summary Introduction

To analyze:

Nonsense suppressors are very inefficient at their function of permitting evaluation of a stop codon. Question asked to conclude the impact on the cell, if nonsense suppressorsremainedeffective at their functions?

Introduction:

Mutation can be defined as a heritable change in DNA sequences. These changes in DNA sequences either leads to evolutionary change in DNA, or it changes the gene sequence which disturbs its desirable function and affects the fitness of the organism. Mutation occurs very rarely and randomly. Gene mutations are rare and random that change DNA sequence and may alter polypeptide composition and protein function. The most common types of gene mutations include substitution, addition, and deletion of one or more DNA base pairs. These types of mutations are limited to a specific base pair or location in a gene and are known as point mutations. Phenotypic effect of these mutationscan be suppressedby another mutation; this process of suppression can be either intergenic or intragenic suppression.