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A vaccine is defined as a preparation of bacterial, viral, or other pathogenic agents or their isolated peptides, which is administered with the objective of eliciting the recipient’s immunity. They are generally categorized into attenuated and inactivated vaccines. In attenuated vaccines, the immune response eliciting agentsare the weakened pathogens that cannot cause disease. They replicate in the recipient’s body and cause mild infection, which usually cannot be detected and elicits an immune response providing long-lasting immunity. Inactivated vaccines have inactivated pathogens as immune response eliciting agent. These agents do not replicate in therecipient’s body.
Immunosuppressed individuals are those individuals that have diminished immune response to antigens due to varied reasons ranging from systematic illness to immunosuppressive treatments. Measles is a viral infection caused by approximately 21 different strains of thevirus. The most common symptoms seen during a measles infection are adry cough, regular sneezing, and watery eyes. The measles, mumps, and rubella (MMR) vaccine are usually administered to prevent measles.
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- Influenza vaccines must be changed yearly because the amino acid sequence of the viral proteins change gradually over time. Based on this information, which is the most logical conclusion? The influenza virusa) is enveloped. b) is non-enveloped.c) has a DNA genome. d) has an RNA genome.e) causes a persistent infection.arrow_forward41) For the successful development of a vaccine to be used against a pathogen, it is necessary that A) the surface antigens of the pathogen do not change. B) a rearrangement of the B cell receptor antibodies takes place. C) all of the surface antigens on the pathogen be identified. D) the pathogen has only one epitope. E) the MHC molecules are heterozygous. 42) In the human disease known as lupus, there is an immune reaction against a patient's own DNA from broken or dying cells, which categorizes lupus as A) an allergy. B) an immunodeficiency. C) an autoimmune disease. D) an antigenic variation. E) a cancer.arrow_forwardA vaccine that employs a toxoid is based upon a ______. A) antibody B) attenuated virus C) histamine D) inactivated form of a bacterial exotoxinarrow_forward
- Which of the following are important for viral protection? Group of answer choices a) Macrophages b)Interferons c)Skin d)Natural Killer lymphocytesarrow_forwardn the "Vaccine Strategies" figure, multiple vaccination options are presented. Select all options below which are options under consideration for the COVID-19 vaccine. A). Injection of a weakened virus B). Injection of an inactive virus. C). Injection of a related coronavirus. D). Injection of genetic material to produce viral proteins directly in the cell.arrow_forwardWhy must a new flu vaccine be manufactured annually? A.) The flu causes mutations in the host cell DNA. B.) Sexual reproduction between flu viruses creates new strains. C.) The genes for the proteins on the exterior of the flu virus mutate frequently. D.) The flu virus develops methods to break down the vaccine.arrow_forward
- Which of the following terms among A-D is not applicable to the body's response to a vaccine? A) O fermentation B) O immunity C) O antigen D) O antibody formation E) O all are applicablearrow_forward46) FcRn are essential for: a) reducing immune inflammation after acute infection b) increasing mast cell activation c) camel immune homeostasis d) absorption of IgG by infants e) none of these 47) An example of a live attenuated viral vaccine currently produced is: a) HIV b) Anthrax c) Polio d) cholera e) all of these 48) C8 is consider: a) an essential early protein in the complement cascade b) an essential late protein in the complement cascade c) an optional early protein in the complement cascade d) an optional late protein in the complement cascade e) more than one of these 49) Mycobacterium often escape CMI by: a) inhibiting TAP b) producing IL-10 c) inhibiting MHC class I production d) destroying NK cells e) inhibiting phagolysosome fusion 50) IL-4 is essential for B cells to switch to: a) IgA b) IgG c) laE d) IgD e) IgMarrow_forwardWhat is the most successful treatment during pregnancy to reduce transmission of HIV from mother to fetus? A) Pre-exposure prophylaxis B) Protease inhibitors C) Reverse transcriptase inhibitors D) Fusion inhibitorsarrow_forward
- During a routine checkup, a 72-year-old patient is advised to receive an influenza vaccine injection. He questions this, saying, “I had one last year. Why do I need another one?” What is an appropriate response from the nurse? a )“The effectiveness of the vaccine wears off after 6 months.”b) “Each year a new vaccine is developed based on the flu strains that are likely to be in circulation.”c )“When you reach 65 years of age, you need boosters on an annual basis.”d) “Taking the flu vaccine each year allows you to build your immunity to a higher level each time.”arrow_forwardLive, attenuated vaccines ________. A) All of the choices are correct. B) contain viable microbes that can multiply in the person C) include the Sabin polio vaccine D) require smaller doses and fewer boosters compared to inactivated vaccines E) include the measles, mumps, rubella vaccine (MMR)arrow_forwardDecreasing the amount of cytokine produced by the body would most directly prevent what event during the progression of COVID-19 in its host? A). Early viral infection of host cells. B). Replication of infected cells. C). Excessive damage to lung cells by the hot immune system. D). Transmission of the virus from one host to another.arrow_forward
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