To draw and name: The amino acids from which alpha keto acids were derived Introduction : An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

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Answer 1

Question

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

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The beta-lactamase hydrolyzes the lactam-ring in penicillin. Describe the mechanism of hydrolysis, insuring to include the involvement of S, D, & K in the reaction sequence. Please help

To map the active site of beta-lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Why doesn't D in this hexapeptide not participate in the hydrolysis of the beta-lactam ring even though S, K, and D are involved in the catalyst?

To map the active site of -lactamase, the enzyme was hydrolyzed with trypsin to yield a hexapeptide (P1) with the following amino acids. Glu, Lys, Leu, Phe, Met, and Ser. Treatment of P1 with phenyl isothiocyanate yielded a PTH derivative of phenylalanine and a peptide (P2). Treatment of P1 with cyanogenbromide gave an acidic tetrapeptide (P3) and a dipeptide (P4).Treatment of P2 with 1-fluoro-2,4-dinitrobenzene, followed by complete hydrolysis, yields N-2,4-dinitrophenyl-Glu. P1, P2, and P3 contain the active site serine. Using the experimental results described above derive the primary sequence of the active site hexapeptide. Please help!

Answer 2

Question

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Expert Solution & Answer

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Answer 3

Question

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Expert Solution & Answer

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Check out a sample textbook solution

See solution

Answer 5

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Answer 6

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

Answer 7

Chapter 18, Problem 21DAP

(a)

Summary Introduction

To draw and name: The amino acids from which alpha keto acids were derived

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids are organic compounds which consist of amine and carboxyl groups. These compounds are organic in nature. The amino acids combine with each other and form a protein structure.

Answer 8

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

Answer 9

(b)

Summary Introduction

To determine: The reason for most likely amino acid precursor of taurine.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Taurine is the amino acid that is majorly found in the tissues of animals. Taurine is an amino acid that is not normally found in proteins. Taurine is often produced as a byproduct of cell damage.

Answer 10

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

Answer 11

(c)

Summary Introduction

To determine: The amino acid that shows significant elevated level in the patient blood in January 1957 and also determine which amino acid is present in the urine of patient.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. Dancis and coauthors concluded that although it appears most likely to the authors that the principal block is in the metabolic degradative pathway of the branched-chain amino acids.

Answer 12

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

Answer 13

(d)

Summary Introduction

To determine: The way in which data presented here supports the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The data include the information about amino acids. Taurine is an amino acid which is not normally found in proteins. The amino acids combine with each other and form a protein structure.

Answer 14

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

Answer 15

(e)

Summary Introduction

To determine: The data which do not fit this model of maple syrup urine disease. Also determine the way in which these different data are contradictory.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children.

Answer 16

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Answer 17

(f)

Summary Introduction

To determine: The data that need to be collected to be more secure in the conclusion.

Introduction:

An autosomal metabolic problem in the body indicates the maple syrup urine disease. This disease directly affects the branched chain amino acids. This situation results in sweet odor in urine. This is mainly seen in the children. The amino acids combine with each other and form a protein structure. Taurine is an amino acid that is not normally found in proteins. The data include the information about the amino acids.

Answer 18

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Answer 19

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Answer 20

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Answer 21

Ch. 18 - Prob. 1P Ch. 18 - Prob. 2P Ch. 18 - Prob. 3P Ch. 18 - Prob. 4P Ch. 18 - Prob. 5P Ch. 18 - Prob. 6P Ch. 18 - Prob. 7P Ch. 18 - Prob. 8P Ch. 18 - Prob. 9P Ch. 18 - Prob. 10P

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