The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn. Concept introduction: Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide . Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Question

Want to see the full answer?

Answer 1

Question

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

please solve this question. It is very sensentive with spelling and characters so if it is "no errors" please be specific. thanks!

Don't used hand raiting and don't used Ai solution

H2(g) + I2(g) ⇔ 2HI(g) Using the above equilibrium, find the equilibrium concentration of H2 if the intial concentration of both H2 and I2 are 2.0. K at this temperature is 55.64.

Answer 2

Question

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Answer 6

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Answer 7

Chapter 18, Problem 18.91P

Interpretation Introduction

Interpretation:

The complete and detailed mechanism for the given example of Wittig-Horner’s reaction is to be drawn.

Concept introduction:

Wittig-Horner's reaction is a similar mechanism like Wittig's reaction. The reaction of a carbonyl compound with stabilized phosphorus ylides or phosphonate carbanions leads to olefins with E-selectivity. Butyl lithium is a strong enough base to deprotonate the carbon and make a carbon nucleophilic that can attack the carbonyl compound in nucleophilic addition. Followed by the nucleophilic addition, the P-O bond produces an intermediate of an epoxide. Reactive ylide gives the final product after the rapid ring opening of the epoxide.

Answer 8

Expert Solution & Answer

Answer 9

Expert Solution & Answer

Answer 10

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 11

Ch. 18 - Prob. 18.1P Ch. 18 - Prob. 18.2P Ch. 18 - Prob. 18.3P Ch. 18 - Prob. 18.4P Ch. 18 - Prob. 18.5P Ch. 18 - Prob. 18.6P Ch. 18 - Prob. 18.7P Ch. 18 - Prob. 18.8P Ch. 18 - Prob. 18.9P Ch. 18 - Prob. 18.10P

Want to see the full answer?

Chapter 18 Solutions