Chemistry for Changing Times
14th Edition
ISBN: 9780134212777
Author: John W. Hill; Terry W. McCreary
Publisher: Pearson Education (US)
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Chapter 18, Problem 18.6CTE
Interpretation Introduction
Interpretation:
A website recommends S-adenosylmethionine (SAMe) for treatment of depression, arthritis, and liver disease.
Concept introduction:
SAM-e is a kind of compound which form naturally in our body and has a vital role for the functioning of our body. SAM-e synthesized form is considered as a supplement within US but it has been sold as a prescribed drugs in most of Europe’s part for years. SAM-e’s scientific name is S-adenosylmethionine.
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a. What is the eluent used in the column chromatography here (a “silica plug filtration” is essentially a very short column)?
b. The spectroscopy of compound 5b is described in the second half of this excerpt, including 1H-NMR and 13C-NMR (which you will learn about in CHEM 2412L), MS (which you will learn about later in CHEM 2411L) and IR. One of the IR signals is at 3530 cm-1. What functional group does this indicate might be present in compound 5b?
Steps and explanations. Also provide, if possible, ways to adress this kind of problems in general.
a. The first three lines of this procedure describe the reaction used to make compound 5b. In the fourth line, hexane and sodium bicarbonate are added. What organic lab technique is being used here?
b. What is the purpose of the Na2SO4?
c. What equipment would you use to “concentrate [a solution] under reduced pressure”?
Chapter 18 Solutions
Chemistry for Changing Times
Ch. 18 - Prob. 1RQCh. 18 - Prob. 2RQCh. 18 - Prob. 3RQCh. 18 - Prob. 4RQCh. 18 - Prob. 5RQCh. 18 - Prob. 6RQCh. 18 - What are prostaglandins? How do prostaglandins...Ch. 18 - Prob. 8RQCh. 18 - Prob. 9RQCh. 18 - Describe a synergistic effect involving drugs.
Ch. 18 - Prob. 11RQCh. 18 - Prob. 12RQCh. 18 - Prob. 13RQCh. 18 - Prob. 14RQCh. 18 - Prob. 15RQCh. 18 - Prob. 16RQCh. 18 - Prob. 17PCh. 18 - Classify the following drugs as natural,...Ch. 18 - Prob. 19PCh. 18 - Prob. 20PCh. 18 - Prob. 21PCh. 18 - Prob. 22PCh. 18 - Prob. 23PCh. 18 - Prob. 24PCh. 18 - Prob. 25PCh. 18 - Prob. 26PCh. 18 - Which of the following was originally marketed as...Ch. 18 - Prob. 28PCh. 18 - Which of the following is not considered to be an...Ch. 18 - How does heroin differ from morphine in its...Ch. 18 - Prob. 31PCh. 18 - How are endorphins related to (a) the anesthetic...Ch. 18 - Prob. 33PCh. 18 - Prob. 34PCh. 18 - Prob. 35PCh. 18 - Prob. 36PCh. 18 - Prob. 37PCh. 18 - Prob. 38PCh. 18 - Prob. 39PCh. 18 - Prob. 40PCh. 18 - Prob. 41PCh. 18 - Prob. 42PCh. 18 - Prob. 43PCh. 18 - Prob. 44PCh. 18 - Prob. 45PCh. 18 - Prob. 46PCh. 18 - Give three differences between hormones and...Ch. 18 - Prob. 48PCh. 18 - Prob. 49PCh. 18 - Prob. 50PCh. 18 - Prob. 51PCh. 18 - Prob. 52PCh. 18 - Prob. 53PCh. 18 - Prob. 54PCh. 18 - Prob. 55PCh. 18 - Prob. 56PCh. 18 - Prob. 57PCh. 18 - Which of the following is often treated with...Ch. 18 - Prob. 59PCh. 18 - Prob. 60PCh. 18 - Prob. 61PCh. 18 - Prob. 62PCh. 18 - Prob. 63PCh. 18 - Prob. 64PCh. 18 - Prob. 65PCh. 18 - Prob. 66PCh. 18 - Prob. 67PCh. 18 - What is an agonist? What is an antagonist?Ch. 18 - Prob. 69PCh. 18 - Prob. 70PCh. 18 - Prob. 71PCh. 18 - What is the difference between drug abuse and drug...Ch. 18 - Review the information on structure and function...Ch. 18 - Prob. 74APCh. 18 - Prob. 75APCh. 18 - Prob. 76APCh. 18 - Prob. 77APCh. 18 - Prob. 78APCh. 18 - Prob. 79APCh. 18 - Prob. 80APCh. 18 - Prob. 81APCh. 18 - Prob. 82APCh. 18 - Prob. 83APCh. 18 - Prob. 84APCh. 18 - Prob. 85APCh. 18 - Prob. 86APCh. 18 - Prob. 87APCh. 18 - Prob. 88APCh. 18 - Prob. 89APCh. 18 - Prob. 90APCh. 18 - Prob. 91APCh. 18 - Prob. 92APCh. 18 - Prob. 93APCh. 18 - Prob. 94APCh. 18 - Prob. 95APCh. 18 - Which of the following compounds are classified as...Ch. 18 - Prob. 97APCh. 18 - Prob. 98APCh. 18 - Prob. 99APCh. 18 - Prob. 100APCh. 18 - Prob. 101APCh. 18 - Prob. 102APCh. 18 - Prob. 103APCh. 18 - Prob. 104APCh. 18 - Prob. 18.1CTECh. 18 - Prob. 18.2CTECh. 18 - Prob. 18.3CTECh. 18 - Prob. 18.4CTECh. 18 - Prob. 18.5CTECh. 18 - Prob. 18.6CTECh. 18 - Prob. 18.7CTECh. 18 - Prob. 18.8CTECh. 18 - Prob. 1CGPCh. 18 - Prob. 2CGPCh. 18 - Prob. 3CGPCh. 18 - Prob. 4CGPCh. 18 - Prob. 5CGPCh. 18 - Prob. 6CGPCh. 18 - Prob. 7CGPCh. 18 - Prob. 8CGPCh. 18 - Prob. 9CGPCh. 18 - Prob. 10CGPCh. 18 - Prob. 11CGPCh. 18 - Prob. 12CGPCh. 18 - Prob. 13CGPCh. 18 - Prob. 14CGPCh. 18 - Prob. 1CHQCh. 18 - Prob. 2CHQCh. 18 - Prob. 3CHQ
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