Chemistry for Changing Times
Chemistry for Changing Times
14th Edition
ISBN: 9780134212777
Author: John W. Hill; Terry W. McCreary
Publisher: Pearson Education (US)
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Chapter 18, Problem 7CGP
Interpretation Introduction

Interpretation:

Prepare a brief reporton an antidepressant, such as sertraline, citalopram, desipramine, isocarboxazid, phenelzine, fluvoxamine, nortriptyline.

Concept introduction:

Antidepressants are drugs used for the treatment of major depressive disorder and other conditions, including dysthymia, anxiety disorders, obsessive−compulsive disorder, eating disorders, chronic pain, neuropathic pain and, in some cases, dysmenorrhea, snoring, migraine, attention-deficit hyperactivity disorder (ADHD), addiction, dependence, and sleep disorders. They may be prescribed alone or in combination with other medications.

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Done 11:14 ⚫ worksheets.beyondlabz.com 5 (a). Using the peak information you listed in the tables for both structures, assign each peak to that portion of the structure that produces the peak in the NMR spectrum. Draw this diagram on your own sheet of paper and attach the sketch of your drawing to this question. Question 6 5 (b). Using the peak information you listed in the tables for both structures, assign each peak to that portion of the structure that produces the peak in the NMR spectrum. Draw this diagram on your own sheet of paper and attach the sketch of your drawing to this question. Question 7 6. Are there any differences between the spectra you obtained in Beyond Labz and the predicted spectra? If so, what were the differences? <
2. Predict the NMR spectra for each of these two compounds by listing, in the NMR tables below, the chemical shift, the splitting, and the number of hydrogens associated with each predicted peak. Sort the peaks from largest chemical shift to lowest. **Not all slots must be filled** Peak Chemical Shift (d) 5.7 1 Multiplicity multiplate .......... 5.04 double of doublet 2 4.98 double of doublet 3 4.05 doublet of quartet 4 5 LO 3.80 quartet 1.3 doublet 6 Peak Chemical Shift (d) Multiplicity
Interpreting NMR spectra is a skill that often requires some amount of practice, which, in turn, necessitates access to a collection of NMR spectra. Beyond Labz Organic Synthesis and Organic Qualitative Analysis have spectral libraries containing over 700 1H NMR spectra. In this assignment, you will take advantage of this by first predicting the NMR spectra for two closely related compounds and then checking your predictions by looking up the actual spectra in the spectra library. After completing this assignment, you may wish to select other compounds for additional practice. 1. Write the IUPAC names for the following two structures: Question 2 Question 3 2. Predict the NMR spectra for each of these two compounds by listing, in the NMR tables below, the chemical shift, the splitting, and the number of hydrogens associated with each predicted peak. Sort the peaks from largest chemical shift to lowest. **Not all slots must be filled**

Chapter 18 Solutions

Chemistry for Changing Times

Ch. 18 - Prob. 11RQCh. 18 - Prob. 12RQCh. 18 - Prob. 13RQCh. 18 - Prob. 14RQCh. 18 - Prob. 15RQCh. 18 - Prob. 16RQCh. 18 - Prob. 17PCh. 18 - Classify the following drugs as natural,...Ch. 18 - Prob. 19PCh. 18 - Prob. 20PCh. 18 - Prob. 21PCh. 18 - Prob. 22PCh. 18 - Prob. 23PCh. 18 - Prob. 24PCh. 18 - Prob. 25PCh. 18 - Prob. 26PCh. 18 - Which of the following was originally marketed as...Ch. 18 - Prob. 28PCh. 18 - Which of the following is not considered to be an...Ch. 18 - How does heroin differ from morphine in its...Ch. 18 - Prob. 31PCh. 18 - How are endorphins related to (a) the anesthetic...Ch. 18 - Prob. 33PCh. 18 - Prob. 34PCh. 18 - Prob. 35PCh. 18 - Prob. 36PCh. 18 - Prob. 37PCh. 18 - Prob. 38PCh. 18 - Prob. 39PCh. 18 - Prob. 40PCh. 18 - Prob. 41PCh. 18 - Prob. 42PCh. 18 - Prob. 43PCh. 18 - Prob. 44PCh. 18 - Prob. 45PCh. 18 - Prob. 46PCh. 18 - Give three differences between hormones and...Ch. 18 - Prob. 48PCh. 18 - Prob. 49PCh. 18 - Prob. 50PCh. 18 - Prob. 51PCh. 18 - Prob. 52PCh. 18 - Prob. 53PCh. 18 - Prob. 54PCh. 18 - Prob. 55PCh. 18 - Prob. 56PCh. 18 - Prob. 57PCh. 18 - Which of the following is often treated with...Ch. 18 - Prob. 59PCh. 18 - Prob. 60PCh. 18 - Prob. 61PCh. 18 - Prob. 62PCh. 18 - Prob. 63PCh. 18 - Prob. 64PCh. 18 - Prob. 65PCh. 18 - Prob. 66PCh. 18 - Prob. 67PCh. 18 - What is an agonist? What is an antagonist?Ch. 18 - Prob. 69PCh. 18 - Prob. 70PCh. 18 - Prob. 71PCh. 18 - What is the difference between drug abuse and drug...Ch. 18 - Review the information on structure and function...Ch. 18 - Prob. 74APCh. 18 - Prob. 75APCh. 18 - Prob. 76APCh. 18 - Prob. 77APCh. 18 - Prob. 78APCh. 18 - Prob. 79APCh. 18 - Prob. 80APCh. 18 - Prob. 81APCh. 18 - Prob. 82APCh. 18 - Prob. 83APCh. 18 - Prob. 84APCh. 18 - Prob. 85APCh. 18 - Prob. 86APCh. 18 - Prob. 87APCh. 18 - Prob. 88APCh. 18 - Prob. 89APCh. 18 - Prob. 90APCh. 18 - Prob. 91APCh. 18 - Prob. 92APCh. 18 - Prob. 93APCh. 18 - Prob. 94APCh. 18 - Prob. 95APCh. 18 - Which of the following compounds are classified as...Ch. 18 - Prob. 97APCh. 18 - Prob. 98APCh. 18 - Prob. 99APCh. 18 - Prob. 100APCh. 18 - Prob. 101APCh. 18 - Prob. 102APCh. 18 - Prob. 103APCh. 18 - Prob. 104APCh. 18 - Prob. 18.1CTECh. 18 - Prob. 18.2CTECh. 18 - Prob. 18.3CTECh. 18 - Prob. 18.4CTECh. 18 - Prob. 18.5CTECh. 18 - Prob. 18.6CTECh. 18 - Prob. 18.7CTECh. 18 - Prob. 18.8CTECh. 18 - Prob. 1CGPCh. 18 - Prob. 2CGPCh. 18 - Prob. 3CGPCh. 18 - Prob. 4CGPCh. 18 - Prob. 5CGPCh. 18 - Prob. 6CGPCh. 18 - Prob. 7CGPCh. 18 - Prob. 8CGPCh. 18 - Prob. 9CGPCh. 18 - Prob. 10CGPCh. 18 - Prob. 11CGPCh. 18 - Prob. 12CGPCh. 18 - Prob. 13CGPCh. 18 - Prob. 14CGPCh. 18 - Prob. 1CHQCh. 18 - Prob. 2CHQCh. 18 - Prob. 3CHQ
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