Given reaction has to be draw completed. Concept Introduction: Acid anhydride can react with water, alcohol and amine . When acid anhydride reacts with water it gives two equivalent of carboxylic acid , with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide. Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Quizzes - Gen Organic & Biological Che... ☆ myd21.lcc.edu + O G screenshot on mac - Google Search savings hulu youtube google disney+ HBO zlib Homework Hel...s | bartleby cell bio book Yuzu Reader: Chemistry G periodic table - Google Search b Home | bartleby 0:33:26 remaining CHEM 120 Chapter 5_Quiz 3 Page 1: 1 > 2 > 3 > 6 ¦ 5 > 4 > 7 ¦ 1 1 10 8 ¦ 9 a ¦ -- Quiz Information silicon-27 A doctor gives a patient 0.01 mC i of beta radiation. How many beta particles would the patient receive in I minute? (1 Ci = 3.7 x 10 10 d/s) Question 5 (1 point) Saved Listen 2.22 x 107 222 x 108 3.7 x 108 2.22 x 108 none of the above Question 6 (1 point) Listen The recommended dosage of 1-131 for a test is 4.2 μCi per kg of body mass. How many millicuries should be given to a 55 kg patient? (1 mCi = 1000 μСi)? 230 mCi

Don't used hand raiting and don't used Ai solution

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 5

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Answer 6

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

Answer 7

Chapter 18, Problem 18.31P

(a)

Interpretation Introduction

Interpretation:

Given reaction has to be draw completed.

Concept Introduction:

Acid anhydride can react with water, alcohol and amine. When acid anhydride reacts with water it gives two equivalent of carboxylic acid, with alcohol it gives carboxylic acid and ester, with amine it gives carboxylate ion and amide.

Amine, water and alcohol acts as a nucleophile and gets attached to the carbonyl carbon of the acid anhydride. The base takes the proton from the from the tetrahedral intermediate. The carboxylate ion gets eliminated from the tetrahedral intermediate to form carboxylic acid derivative.

Answer 8

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

Answer 9

(b)

Interpretation Introduction

Interpretation:

Given reaction has to be completed.

Concept Introduction:

Reaction of acid chloride with ammonia or amines:

The reaction of acid chlorides with ammonia and primary and secondary amines will yield amide.

The nucleophilic addition of ammonia or amine to the carbonyl carbon occurs which is followed by a proton transfer forming an addition intermediate that will eliminate chloride and lose a proton to give the amide compound.

Answer 10

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Answer 11

(c)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Answer 12

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Answer 13

(d)

Interpretation Introduction

Interpretation:

Given reaction has to be draw and completed.

Concept Introduction:

Reaction of an ester with ammonia or an amine:

Treatment of an ester with ammonia or a primary or secondary amine gives an amide.

The nucleophilic addition of the ammonia or amine to the carbonyl carbon occurs followed by a proton transfer and a tetrahedral addition intermediate is formed. The intermediate can directly alkoxide and lose a proton to the alkoxide to give products.

Answer 14

Expert Solution & Answer

Answer 15

Expert Solution & Answer

Answer 16

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 17

Ch. 18.1 - Prob. 18.1P Ch. 18.2 - Prob. 18.2P Ch. 18.4 - Prob. 18.3P Ch. 18.4 - Prob. 18.4P Ch. 18.4 - Synthesis of nitriles by nucleophilic displacement...Ch. 18.5 - Complete the following transesterification...Ch. 18.6 - Complete and balance equations for the following...Ch. 18.8 - Prob. AQ Ch. 18.8 - Several compounds have been found to inhibit...Ch. 18.8 - Prob. CQ

Solution Summary: The author explains that acid anhydride can react with water, alcohol, and amine. The nucleophilic addition of ammonia to the carbonyl carbon is followed by a proton transfer.

Videos

Want to see the full answer?

Chapter 18 Solutions