(a) Interpretation: The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated. Concept introduction: The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

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need help please and thanks dont understand only need help with C-F Learning Goal: As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT. The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7). Part A - Difference in binding free eenergies Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol. The margin of error is 2%. Part B - Compare difference in free energy to the thermal…

Answer 1

Question

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

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need help please and thanks dont understand only need help with C-F Learning Goal: As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT. The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7). Part A - Difference in binding free eenergies Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol. The margin of error is 2%. Part B - Compare difference in free energy to the thermal…

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need help please and thanks dont understand a-b Learning Goal: As discussed during the lecture, the enzyme HIV-1 reverse transcriptae (HIV-RT) plays a significant role for the HIV virus and is an important drug target. Assume a concentration [E] of 2.00 µM (i.e. 2.00 x 10-6 mol/l) for HIV-RT. Two potential drug molecules, D1 and D2, were identified, which form stable complexes with the HIV-RT. The dissociation constant of the complex ED1 formed by HIV-RT and the drug D1 is 1.00 nM (i.e. 1.00 x 10-9). The dissociation constant of the complex ED2 formed by HIV-RT and the drug D2 is 100 nM (i.e. 1.00 x 10-7). Part A - Difference in binding free eenergies Compute the difference in binding free energy (at a physiological temperature T=310 K) for the complexes. Provide the difference as a positive numerical expression with three significant figures in kJ/mol. The margin of error is 2%. Part B - Compare difference in free energy to the thermal energy Divide the…

Answer 2

Question

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

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Answer 3

Question

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

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Answer 4

Question

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

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Answer 5

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

Answer 6

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Answer 7

Chapter 18, Problem 18.19E

Interpretation Introduction

(a)

Interpretation:

The equation for the reaction of Lipase-catalyzed hydrolysis of oil is to be stated.

Concept introduction:

The hydrolysis of the triglycerides in the fat cells results in the formation of fatty acids and glycerol. Lipase-catalyzed hydrolysis involves the hydrolysis of the fats and oils in the presence of lipase catalyst to form glycerol and fatty acids.

Answer 8

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Answer 9

Interpretation Introduction

(b)

Interpretation:

The equation for the reaction of saponification of oil is to be stated.

Concept introduction:

The reaction of an ester with a strong base is called saponification reaction. In saponification reaction, the ester bond breaks and results into two products: the salt of carboxylic acid and an alcohol.

Answer 10

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

Answer 11

Interpretation Introduction

(c)

Interpretation:

The equation for the reaction of hydrogenation of oil is to be stated.

Concept introduction:

The addition of H2 in the presence of catalyst is known as catalytic hydrogenation reaction. This is a syn addition. Hydrogenation reaction is exothermic in nature due to the fact that the bonds are stronger in product than in the reactant.

Answer 12

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Solution Summary: The author explains the equation for the reaction of Lipase-catalyzed hydrolysis of oil.

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