ANAT.+PHYSIO.1-LAB.MAN. >CUSTOM<
20th Edition
ISBN: 9781264303106
Author: VanPutte
Publisher: MCGRAW-HILL HIGHER EDUCATION
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 17.4, Problem 24AYP
What two ways can a membrane-bound receptor use to activate cellular response?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
You perform a competition study on a GPCR. You have isolated the plasma membrane
from cells which contains the GPCR of interest. If an agonist and an inverse agonist
are at equal concentrations in your study but the inverse agonist has a 10 x higher
affinity for the receptor than the agonist, what would you expect to be the overall
outcome to be?
More of the agonist is bound and so most of the receptor is in its active conformation and is
stimulated
More of the inverse agonist is bound and so most of the receptor is in its inactive
conformation and is unstimulated.
Do you consider GPCR is intracellular or membrane bound receptor?? Explain it
A) Please explain what a G protein coupled receptor is. Please explain how G protein interacts with this receptor.
B) Please explain the kind of reactions that follow binding a specific ligand to a G protein coupled receptor. What do these reactions do in the cell?
C) How do these reactions work in the cell. What is the function of these reactions in the cell? How do the reactions proceed?
Chapter 17 Solutions
ANAT.+PHYSIO.1-LAB.MAN. >CUSTOM<
Ch. 17.1 - How does an endocrine gland differ from an...Ch. 17.1 - Prob. 2AYPCh. 17.1 - In what ways does the nervous system differ from...Ch. 17.1 - Name and describe the four classes of chemical...Ch. 17.2 - Prob. 5AYPCh. 17.2 - Prob. 6AYPCh. 17.2 - Prob. 7AYPCh. 17.2 - What effect does a bound hormone have on the...Ch. 17.2 - What are the two chemical categories of hormones?...Ch. 17.2 - Describe how the chemical nature of a hormone...
Ch. 17.2 - Prob. 11AYPCh. 17.2 - Why do organs regulated by protein hormones have...Ch. 17.2 - Prob. 13AYPCh. 17.2 - Describe chronic, acute, and episodic patterns of...Ch. 17.3 - Describe and give examples of the three major ways...Ch. 17.3 - Prob. 16AYPCh. 17.4 - What characteristics ofa hormone receptor make...Ch. 17.4 - What is down-regulation, and what may cause it to...Ch. 17.4 - Prob. 19AYPCh. 17.4 - What are the two classes of hormone receptors? How...Ch. 17.4 - Prob. 21AYPCh. 17.4 - Prob. 22AYPCh. 17.4 - Prob. 23AYPCh. 17.4 - What two ways can a membrane-bound receptor use to...Ch. 17.4 - Explain how the hormone-receptor complex can alter...Ch. 17.4 - List four intracellular mediators affected by G...Ch. 17.4 - Prob. 27AYPCh. 17.4 - Prob. 28AYPCh. 17.4 - Prob. 29AYPCh. 17.4 - Prob. 30AYPCh. 17 - Prob. 1RACCh. 17 - Prob. 2RACCh. 17 - Which of these can regulate the secretion of a...Ch. 17 - Prob. 4RACCh. 17 - Prob. 5RACCh. 17 - Concerning the half-lifeof hormones, a....Ch. 17 - Prob. 7RACCh. 17 - Prob. 8RACCh. 17 - Prob. 9RACCh. 17 - Prob. 10RACCh. 17 - Prob. 11RACCh. 17 - Which of these can limit a cell's response to a...Ch. 17 - Prob. 13RACCh. 17 - Prob. 14RACCh. 17 - When a hormone binds to a nuclear receptor a. DNA...Ch. 17 - Prob. 16RACCh. 17 - Prob. 1CTCh. 17 - Prob. 2CTCh. 17 - Prob. 3CTCh. 17 - Prob. 4CTCh. 17 - Prob. 5CTCh. 17 - Prob. 6CTCh. 17 - Thyroid hormones are important in regulating the...Ch. 17 - Prob. 8CTCh. 17 - Prob. 9CT
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Which receptor undergoes clustering and autophosphorylation in response to activation by a signal? Group of answer choices: a)Ligand-gated ion channels b)Receptor Tyrosine Kinases (RTKs) c)G-Protein Coupled Receptors (GPCRs) d)Nuclear Receptorsarrow_forwardName and define (briefly) the four different types of receptors involved in Cellsignaling. Give an example of a ligand and specific type of receptor (where would you find the receptor?) for one of the receptors defined.arrow_forwardWhat are the three types of cell signal receptors found in the plasma membrane?arrow_forward
- What is the three-dimensional structure of GPCRs? How does the structure of these receptors determine their functions?arrow_forwardWhich of the following statements is false? Question 11 options: a) Nucleotides and amino acids can act as extracellular signal molecules. b) Some signal molecules can bind directly to intracellular proteins that bind DNA and regulate gene transcription. c) Some signal molecules are transmembrane proteins. d) Dissolved gases such as nitric oxide (NO) can act as signal molecules, but because they cannot interact with proteins they must act by affecting membrane lipids.arrow_forwardMembrane channels and carriers both show changes in protein conformation. What is the role of such conformation changes in: (1) channels, and (2) carriers?arrow_forward
- Gap junctions and tunneling nanotubes are two distinct types of direct intracellular communication. In comparing and contrasting gap junctions and tunneling nanotubes, which of the following statements is true? gap junctions provide a portal for small molecules, proteins and small organelles to move from cell to cell, tunneling nanotubes only permit small molecules to pass between cells typically, there are only two gap junctions that exist between adjacent cells that are communicating via this mechanism; on the other hand, there are many tunneling nanotubes between communicating cells both gap junctions and tunneling nanotubes can pass small molecules between cells none of the above is truearrow_forwardDefine membrane-bound receptorarrow_forwardEndothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium. They have an important role in vascular homeostasis. Endothelin activates G protein-coupled receptors (GPCRs) ETA or ETB on a target cell. Which subunit of heterotrimeric G protein is released when the receptor is activated? a.) gamme b.) beta c.) alphaarrow_forward
- What are the features of Receptor?arrow_forwardThe Structure of the acetylcholine receptor is shown below: A. Knowing the amino acid sequence of this protein, what tool would you use to identify the membrane-spanning region? Explain how it works.arrow_forwardCompare and contrast GPCR and RTK receptors with respect to (a)structure (especially the transmembrane region), (b) activation mechanism, and (c) initial signal transduction across the membrane.arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Intro to Cell Signaling; Author: Amoeba Sisters;https://www.youtube.com/watch?v=-dbRterutHY;License: Standard youtube license