Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 17, Problem 9MCQ
Summary Introduction
Introduction:
The cell mediated immune response is mediated by T lymphocytes, which participates in the phagocytosis, Natural killer cells (NK), formation of cytotoxic T lymphocytes and releases cytokines for antigen response. The main function of the cell mediated immune response is to detect and eliminate the intracellular pathogens by phagocytosis, delayed hypersensitivity, anti-viral immunity, graft rejection and graft versus host disease.
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For question with blanks, choose the combination of answers that most accurately completes the statement.Helper T cells receive antigen from.......... , and cytotoxic T cells receive antigen from............. a. macrophages, B cells b. class II MHC, class I MHC c. viruses, bacteria d. class I MHC, class II MHC
Which of the following statements pertain to this cell. This cell is a precursor to a cell which:
1. is an antigen-presenting cell
2. demonstrates MHC I molecules
3. demonstrates MHC II molecules
4. demonstrates CD4 molecules
5. is capable of synthesizing and releasing perforin and granzymes
Choose from the following:
(A) 1, 2, and 3
(B) 2 and 3 only
(C) 3 and 4 only
(D) 1 and 3
(E) 1, 4, and 5
Dendritic cells take up, process or present antigen by all of the following routes except
Select one:
a. receptor-mediated endocytosis of bacteria.
b.
macropinocytosis of bacteria or viruses.
c. uptake of viruses using Toll-like receptor TLR9.
d.
cross-presentation from the MHC class II pathway to the MHC class I pathway.
Oe. cross-presentation from incoming infected dendritic cells to healthy resident dendritic cells in secondary
lymphoid tissue.
Of. delivery of viral peptides from cytosol to endoplasmic reticulum during viral infection.
Chapter 17 Solutions
Microbiology: An Introduction
Ch. 17 - Contrast the terms in the following pairs: a....Ch. 17 - What does MHC stand for? What is the function of...Ch. 17 - Why is dietary protein deficiency associated with...Ch. 17 - Prob. 4RCh. 17 - Prob. 5RCh. 17 - DRAW IT a. In the graph below, at time A the host...Ch. 17 - How would each of the following prevent infection?...Ch. 17 - Prob. 8RCh. 17 - Explain why a person who recovers from a disease...Ch. 17 - Prob. 10R
Ch. 17 - Prob. 1MCQCh. 17 - The type of protection provided by the injection...Ch. 17 - Prob. 3MCQCh. 17 - Prob. 4MCQCh. 17 - Prob. 5MCQCh. 17 - Prob. 6MCQCh. 17 - Prob. 7MCQCh. 17 - Prob. 8MCQCh. 17 - Prob. 9MCQCh. 17 - Prob. 10MCQCh. 17 - Prob. 1ACh. 17 - Why is dietary protein deficiency associated with...Ch. 17 - A positive tuberculin skin test shows cellular...Ch. 17 - On her vacation to Australia, Janet was bitten by...Ch. 17 - Prob. 1CAECh. 17 - Prob. 2CAECh. 17 - A patient with chronic diarrhea was found to lack...Ch. 17 - Newborns (under 1 year) who contract dengue have a...
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- A patient has contracted an upper respiratory infection caused by a virus. Her initial adaptive immune response to the virus is due to what mechanism of immune surveillance?a. The display of viral antigens by naïve B-cells on class I MHC, which is then recognized by helper T-cells that then activate cytotoxic T-cells.b. The display of viral antigens on class I MHC, which is then displayed to sensitized naïve B-cells, leading to the production of antibodies.c. The display of viral antigens on class II MHC by a sensitized naïve B-cell, which is then activated by a helper T-cell primed to the same antigen to begin producing antibodies.d. The display of viral antigens on class I MHC, which is then displayed to helper T-cells, leading to the activation of naïve cytotoxic T-cells.arrow_forwardWhich of the following statements are true for antigen presentation. a. Antigen presentation means that other cells attach the pathogen first and present it to T cells. b. Antigen-presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor to B cells c. Antigen presenting cells display protein fragments, resulting from the digestion of the pathogen, in complex with MHC receptor on their surface. d. Antigen-presenting cells are phagocytic cells e. Antigen presentation is required for T cell activation f. Cytokines released by macrophages are required for T cell activation g. T cell receptors recognize the MHC receptors in complex with antigen fragments displayed by antigen-presenting cells. h. Phagocytic cells are involved in innate immunity. Therefore they have no role in T-cell activationarrow_forwardHuman immune system a) Pathogen-associated molecular patterns are conserved molecular structures produced by microorganisms, but not by host cells. b) A virus-infected host cell that displays a viral antigen via MHC class I molecules may become a target of cytotoxic T cells. c) Secreted MHC Class I proteins present in blood plasma can function as opsonins. d) Both (a) and (b) are correct and (c) is incorrect e) Statements (a), (b) and (c) are all correctarrow_forward
- Which of the following explains why dendritic cells, but not macrophages or B cells, contribute to the activation of naive T cells? a. Macrophages and B cells do not express MHC class II molecules until they are activated. b. Dendritic cells upregulate B7 after engaging innate immunity receptors at sites of infection. c. Dendritic cells express higher levels of CTLA4. d. Macrophages and B cells do not process antigen. e. Dendritic cells use Toll-like receptors to hold antigen in place for extended periods of time.arrow_forwardCHAPTER 20 The Lymphatic System and Immunity Matching SECTION 3 Revie w Match each lettered term with the most closely related description. a. opsonization 1 b. helper T cells Two parallel pairs of polypeptide chains Found on helper T cells C. antibody d. class II MHC 3 Active and passive 4 Transfer of antibodies e. costimulation Attacked by HIV f. IgM 6 Enhances phagocytosis g. class I MHC h. IgG 7 MHC proteins present in the plasma membranes of all nucleated cells i. passive immunity j. anaphylaxis 8 Differentiate into memory and plasma cells 9 MHC proteins present in the plasma membranes of all APCS and lymphocytes 9 k. CD4 markers 10 I. acquired immunity 10 Antibodies used to determine blood type 11 m. B lymphocytes 11 Secondary binding process required for T cell activation 12 12 Accounts for 80 percent of all immunoglobulins 13 13 Circulating allergen stimulates mast cells throughout body Match each lettered term with thearrow_forwardIndicate to which branch(es) of the immune system the following statements apply, using H for the humoral branch and CM for the cell-mediated branch. Some statements may apply to both branches (B). a. Involves B cells b. Involves T cells c. Responds to extracellular bacterial infection d. Involves secreted antibody e. Kills virus-infected self cellsarrow_forward
- Antigen presenting cells with antigen present on MHC II bind to CD4 cells with compatible receptors, and the APC releases cytokines causing the CD4 cells to activate and differentiate into plasma cells. O 1) True O 2) Falsearrow_forwardWhich of the following cells demonstrate MHC II molecules on their surface membrane? 1. B lymphocyte 2. macrophage 3. erythrocyte 4. neuron 5. smooth muscle cell Choose from the following: (A) 1 and 2 (B) 1, 2 and 3 (C) 1, 2, 4, and 5 (D) 1, 2, 3, 4, and 5arrow_forwardAPC cells with antigen presented on MHC I can trigger which naïve cell type to activate, thus forming memory and effector cells? O 1) macrophages O 2) CD4 cells O 3) CD8 cells O 4) B cellsarrow_forward
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