HUMAN PHYSIO W/ APR & PHILS (LL) PKG
15th Edition
ISBN: 9781265382353
Author: Fox
Publisher: MCGRAW-HILL HIGHER EDUCATION
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Question
Chapter 17, Problem 30RA
Summary Introduction
To review:
The location of macula densa and its role in regulation of rennin secretion and tubuloglomerular feedback.
Introduction:
The kidneys are engaged in the process of blood filtration as well as excretion of the wastes in the urine. Various parts of a kidney perform different functions to accomplish its functions. The juxtaglomerular apparatus is responsible for regulating the function of each nephron.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Match the letter labels in the figure below to the terms. Some letter
labels are not used.
MNNNNNNIN
M
C
B
A
M
D
F
E
H
K
G
8
The diagram below illustrates a quorum sensing pathway from Staphylococcus aureus. Please answer the following questions.
1. Autoinduction is part of the quorum sensing system. Which promoter (P2 or P3) is critical for autoinduction?
2)This staphylococcus aureus grows on human wounds, causing severe infections. You would like to start a clinical trial to treat these wound infections. Please describe:
a) What molecule do you recommend for the trial. Why?
b) Your trial requires that Staphylococcus aureus be isolated from the wound and submitted to genome sequencing before admittance. Why? What are you testing for?
3) If a mutation arises where the Promoter P3 is constitutively active, how would that influence sensitivity to AIP? Please explain your rationale.
4) This pathway is sensitive to bacterial cell density. Describe two separate mutation that would render the pathway active independent of cell density. Briefly explain your rationale.
Mutation 1
Mutation 2
Chapter 17 Solutions
HUMAN PHYSIO W/ APR & PHILS (LL) PKG
Ch. 17 - Describe the "theme" of kidney function in a...Ch. 17 - Draw and label the tubular components of a nephron...Ch. 17 - Trace the course of tubular fluid from the...Ch. 17 - Trace the course of blood flow through the kidney...Ch. 17 - Describe the structures that plasma fluid must...Ch. 17 - Describe the forces that affect the formation of...Ch. 17 - Explain the significance of the glomerular...Ch. 17 - Prob. 5bCPCh. 17 - Describe the mechanisms for salt and water...Ch. 17 - Compare the transport of and water across the...
Ch. 17 - Describe the interaction between the ascending and...Ch. 17 - Explain how ADH helps the body conserve water. How...Ch. 17 - Define renal plasma clearance and describe how...Ch. 17 - Define the terms reabsorption and secretion. Using...Ch. 17 - Explain why the total renal blood flow can be...Ch. 17 - Define transport maximum and renal plasma...Ch. 17 - Describe the effects of aldosterone on the renal...Ch. 17 - Prob. 11bCPCh. 17 - Explain the mechanisms by which the cortical...Ch. 17 - Explain how the kidneys reabsorb filtered...Ch. 17 - Suppose a person with diabetes mellitus had an...Ch. 17 - List the different categories of clinical...Ch. 17 - Explain why most diuretics can cause excessive...Ch. 17 - Define uremia and discuss the dangers associated...Ch. 17 - Which of these statements about the renal pyramids...Ch. 17 - Match the following items:
Active transport of...Ch. 17 - Match the following items:
Active transport of...Ch. 17 - Match the following items:
Passively permeable to...Ch. 17 - Match the following items:
Passively permeable to...Ch. 17 - Antidiuretic hormone promotes the retention of...Ch. 17 - Aldosterone stimulates sodium reabsorption and...Ch. 17 - Substance X has a clearance greater than zero but...Ch. 17 - Prob. 9RACh. 17 - About of the glomerular ultrafiltrate is...Ch. 17 - Diuretic drugs that act in the nephron loop...Ch. 17 - The appearance of glucose in the urine a. occurs...Ch. 17 - Reabsorption of water through the tubules occurs...Ch. 17 - Which of these factors oppose(s) filtration from...Ch. 17 - The countercurrent exchange in the vasa recta...Ch. 17 - The kidneys help to maintain acid-base balance...Ch. 17 - Scientists currently believe that the main barrier...Ch. 17 - A drug that blocks the action of the organic anion...Ch. 17 - Explain how glomerular ultra filtrate is produced...Ch. 17 - Describe the transport properties of the nephron...Ch. 17 - Prob. 21RACh. 17 - Prob. 22RACh. 17 - Prob. 23RACh. 17 - Prob. 24RACh. 17 - Identify where secretion occurs in the nephron,...Ch. 17 - Which diuretic drugs do not produce hypokalemia?...Ch. 17 - Prob. 27RACh. 17 - Prob. 28RACh. 17 - Prob. 29RACh. 17 - Prob. 30RACh. 17 - Prob. 31RACh. 17 - Prob. 32RACh. 17 - s Suppose a woman with a family history of...Ch. 17 - Prob. 34RACh. 17 - Prob. 35RACh. 17 - Prob. 36RACh. 17 - Prob. 37RACh. 17 - Prob. 38RACh. 17 - Prob. 39RACh. 17 - Prob. 40RACh. 17 - Prob. 41RACh. 17 - Prob. 42RA
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