EP FUND.OF GENERAL,ORG...-MOD.MASTERING
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Chapter 17, Problem 17.66AP
LSD (lysergic acid diethylamide), a semisynthetic psychedelic drug of the ergoline family, has the structure shown here. Identify the
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From the reaction data below, determine whether the reaction is first order or second order and calculate the rate constant.
Time (s)
0
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5.4
1
4.6
2
3.9
3
3.2
4
2.7
5
2.3
Only a plot of In[reactant] versus t gives a straight line, so the reaction is
first order
. The negative of the slope, k, is
0.171
Hair grows at a rate of about 20 cm/yr. All this growth is concentrated at the base of the hair fiber, where a-keratin filaments are
synthesized inside living epidermal cells and assembled into ropelike structures.
Two-chan
14
Protofilament
20-30 A
Two-chain
Intermediate
flament
-Protob
Protofilament
Cross section of a hair
The fundamental structural element of a keratin is the a helix, which has 3.6 amino acid residues per turn and a rise of 5.4 A
perlum.
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Amino terminus
Carbon
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Carboxyl terminus
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0422
rate of peptide bond formation:
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Specific rotation is a measure of a solution's capacity to rotate circularly polarized light. The unfolding of the a helix of a
polypeptide to a random conformation is accompanied by a large decrease in specific rotation.
Polyglutamate, a polypeptide made up of only 1-Glu residues, has the a helix conformation at pH 3. When researchers raise the
pH to 7, there is a large decrease in the specific rotation of the solution. Similarly, polylysine (1.-Lys residues) is an a helix at pH
10, but when researchers lower the pH to 7 the specific rotation also decreases, as shown in the graph.
a Helix
Specific rotation
Poly(Glu)
a Helix
Random
conformation
Poly(Lys)
Random conformation
T
+
°
2
4
6 В
10 12 14
PH
Complete the statements about the molecular mechanism for these changes in specific rotation.
Increasing the pH of a polyglutamate solution from 6 to 7 causes the carboxyl group of each glutamate residue
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Chapter 17 Solutions
EP FUND.OF GENERAL,ORG...-MOD.MASTERING
Ch. 17.1 - Identify the following molecules as a carboxylic...Ch. 17.1 - Prob. 17.2PCh. 17.1 - Prob. 17.3PCh. 17.1 - Prob. 17.4PCh. 17.1 - Prob. 17.5PCh. 17.1 - Prob. 17.6PCh. 17.1 - In the following pairs of compounds, which would...Ch. 17.1 - Write both condensed and line structures for (a)...Ch. 17.1 - Prob. 17.9PCh. 17.1 - Draw structures corresponding to these names: (a)...
Ch. 17.1 - Prob. 17.11PCh. 17.1 - Prob. 17.12PCh. 17.1 - Prob. 17.13KCPCh. 17.2 - Salsalate, which is an ester formed by the...Ch. 17.2 - Prob. 17.2CIAPCh. 17.2 - Prob. 17.3CIAPCh. 17.2 - Prob. 17.14PCh. 17.2 - Prob. 17.15PCh. 17.2 - Prob. 17.16PCh. 17.3 - Prob. 17.17PCh. 17.3 - Raspberry oil contains an ester that is made by...Ch. 17.3 - Prob. 17.19PCh. 17.3 - Prob. 17.20PCh. 17.3 - Prob. 17.21PCh. 17.4 - If a bottle of aspirin tablets has the aroma of...Ch. 17.4 - Prob. 17.23PCh. 17.4 - What carboxylic acids and amines result from...Ch. 17.5 - Prob. 17.25PCh. 17.5 - Prob. 17.26KCPCh. 17.6 - Prob. 17.27PCh. 17.6 - Prob. 17.28PCh. 17.6 - Prob. 17.4CIAPCh. 17.6 - Prob. 17.5CIAPCh. 17.6 - Prob. 17.29PCh. 17 - Prob. 17.30UKCCh. 17 - Prob. 17.31UKCCh. 17 - One phosphorylated form of glycerate is...Ch. 17 - Prob. 17.33UKCCh. 17 - Prob. 17.34UKCCh. 17 - Prob. 17.35UKCCh. 17 - Prob. 17.36UKCCh. 17 - For the following compounds, give the systematic...Ch. 17 - Write the equation for the ionization of hexanoic...Ch. 17 - Prob. 17.39APCh. 17 - Prob. 17.40APCh. 17 - Prob. 17.41APCh. 17 - Give systematic names for the following carboxylic...Ch. 17 - Give systematic names for the following carboxylic...Ch. 17 - Prob. 17.44APCh. 17 - Prob. 17.45APCh. 17 - Draw structures corresponding to the following...Ch. 17 - Draw structures corresponding to the following...Ch. 17 - Malic acid, a dicarboxylic acid found in apples,...Ch. 17 - Prob. 17.49APCh. 17 - Prob. 17.50APCh. 17 - Prob. 17.51APCh. 17 - Prob. 17.52APCh. 17 - Prob. 17.53APCh. 17 - Give systematic names for the following structures...Ch. 17 - Give systematic names for the following structures...Ch. 17 - Prob. 17.56APCh. 17 - Prob. 17.57APCh. 17 - Give systematic names for the following structures...Ch. 17 - Give systematic names for the following structures...Ch. 17 - Prob. 17.60APCh. 17 - What compounds are produced from hydrolysis of...Ch. 17 - Procaine, a local anesthetic whose hydrochloride...Ch. 17 - Prob. 17.63APCh. 17 - Lactones are cyclic esters in which the carboxylic...Ch. 17 - When both the carboxylic acid and the amine are in...Ch. 17 - LSD (lysergic acid diethylamide), a semisynthetic...Ch. 17 - Prob. 17.67APCh. 17 - Prob. 17.68APCh. 17 - Prob. 17.69APCh. 17 - Prob. 17.70APCh. 17 - Prob. 17.71APCh. 17 - Prob. 17.72APCh. 17 - Prob. 17.73APCh. 17 - Prob. 17.74APCh. 17 - Prob. 17.75APCh. 17 - Three amide isomers, N,N-dimethylformamide,...Ch. 17 - Prob. 17.77CPCh. 17 - Prob. 17.78CPCh. 17 - Mention at least two simple chemical tests by...Ch. 17 - Prob. 17.80CPCh. 17 - Name the following compounds.Ch. 17 - Each of the following materials has an ester that...Ch. 17 - Prob. 17.83GPCh. 17 - Prob. 17.84GP
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