Chapter 16, Problem 5Q

Summary Introduction

To review:

The possible consequences of phorbol esters in an initiated cell and the enzymes activated by phorbol esters and DAG.

Introduction:

Cancer is a multistage process and it initiates with initiating events usually viral infection or exposure to a carcinogen. These initial events are then followed by contact with tumor promoters. Tumor promoters are chemical molecules that activate cell proliferation; however, they do not have the ability to initiate the formation of a tumor on their own.