The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP. Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

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Answer 1

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Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

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Answer 2

Question

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

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Answer 3

Question

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Expert Solution & Answer

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Answer 4

Question

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

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Answer 5

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Answer 6

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Answer 7

Chapter 16, Problem 3Q

Summary Introduction

To explain: The consequences of a mutation in the α-subunit of G protein which causes the reduction in its affinity for GDP and not GTP.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Answer 8

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Answer 9

Summary Introduction

To explain: The comparison of the Gα-subunit with cholera toxin.

Introduction: G proteins are of two types: monomeric G proteins and trimeric G proteins. GPCR belongs to the class of trimeric G proteins. It has three subunits α, β and γ. Gα subunit has GTP hydrolysis activity and has the major role after ligand binding. GPCR is the most abundant G protein type receptor in which several ligands like hormones, neurotransmitters and several other proteins bind to. GPCR has a 7 transmembrane domain and belongs to Class Type IV receptors. It is also involved in the signaling of sense organs which includes vision, olfactory, touch, and taste.

Answer 10

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Answer 13

Ch. 16 - Prob. 1Q Ch. 16 - Prob. 2Q Ch. 16 - Prob. 3Q Ch. 16 - Prob. 4Q Ch. 16 - Prob. 5Q Ch. 16 - Prob. 6Q Ch. 16 - Prob. 7Q Ch. 16 - Prob. 8Q Ch. 16 - Prob. 9Q Ch. 16 - Prob. 10Q

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