The ways in which an intracellular signaling protein can amplify its signal as it relays onward. Concept introduction: The large steroid hormones and the protein hormones bind to their respective extracellular receptor site of the transmembrane receptor and initiate a cascade inside the cell. Inside the cell, the cascade or downstream process is carried out with the help of intracellular signaling molecule. These intracellular signaling molecules activate or generate the next signaling molecule in the cascade, and the cascade continues until a new cytoskeleton configuration is initiated or a gene is switched on or off or a metabolic enzyme is activated. The intracellular signaling molecules detect, relay, amplify, and distribute the signal during the cascade.

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Chapter 16, Problem 2Q

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To explain: The ways in which an intracellular signaling protein can amplify its signal as it relays onward.

Concept introduction: The large steroid hormones and the protein hormones bind to their respective extracellular receptor site of the transmembrane receptor and initiate a cascade inside the cell. Inside the cell, the cascade or downstream process is carried out with the help of intracellular signaling molecule. These intracellular signaling molecules activate or generate the next signaling molecule in the cascade, and the cascade continues until a new cytoskeleton configuration is initiated or a gene is switched on or off or a metabolic enzyme is activated. The intracellular signaling molecules detect, relay, amplify, and distribute the signal during the cascade.

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