Fundamentals of Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134477336
Author: Martini
Publisher: PEARSON
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Chapter 16, Problem 31RQ
Summary Introduction
To determine:
The neurotransmitter to which the given molecule is mimicking and also the receptors to which it is binding.
Concept introduction:
The sympathetic nervous system releases norepinephrine as neurotransmitter at the target organs and tissues, to produce the desired physiological effects. The norepinephrine binds to adrenergic receptors on the plasma membrane and activates the G-protein. The G-protein then produces the effects through the second messengers and other intermediaries.
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When the neurotransmitter acetylcholine (ACh) binds the acetylcholine receptor (a GPCR) on muscle cells, it causes them to contract. ZIGGY, a chemical analog of ACh, also binds to the same acetylcholine receptor on muscle cells, but instead causes the muscle cells to relax. For this reason, it is sometimes prescribed as a muscle relaxer. Explain in 3-4 sentences how ZIGGY could cause muscle relaxation.
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Chapter 16 Solutions
Fundamentals of Anatomy & Physiology (11th Edition)
Ch. 16 - Prob. 1CPCh. 16 - Prob. 2CPCh. 16 - Prob. 3CPCh. 16 - Prob. 4CPCh. 16 - Prob. 5CPCh. 16 - Prob. 6CPCh. 16 - Prob. 7CPCh. 16 - Prob. 8CPCh. 16 - Prob. 9CPCh. 16 - Prob. 10CP
Ch. 16 - Name the two types of cholinergic receptors on the...Ch. 16 - Prob. 12CPCh. 16 - Prob. 13CPCh. 16 - Prob. 14CPCh. 16 - Prob. 15CPCh. 16 - Prob. 16CPCh. 16 - Prob. 17CPCh. 16 - Prob. 18CPCh. 16 - Prob. 19CPCh. 16 - Prob. 20CPCh. 16 - Prob. 21CPCh. 16 - Prob. 22CPCh. 16 - Prob. 23CPCh. 16 - Prob. 24CPCh. 16 - Prob. 25CPCh. 16 - Prob. 26CPCh. 16 - Prob. 27CPCh. 16 - Prob. 28CPCh. 16 - Prob. 1RQCh. 16 - Prob. 2RQCh. 16 - Prob. 3RQCh. 16 - Prob. 4RQCh. 16 - Prob. 5RQCh. 16 - Prob. 6RQCh. 16 - Prob. 7RQCh. 16 - What are the components of a visceral reflex arc?Ch. 16 - Prob. 9RQCh. 16 - Prob. 10RQCh. 16 - Prob. 11RQCh. 16 - All preganglionic autonomic fibers release _____...Ch. 16 - Prob. 13RQCh. 16 - Prob. 14RQCh. 16 - Prob. 15RQCh. 16 - Prob. 16RQCh. 16 - Prob. 17RQCh. 16 - Prob. 18RQCh. 16 - Prob. 19RQCh. 16 - Prob. 20RQCh. 16 - Prob. 21RQCh. 16 - Prob. 22RQCh. 16 - Prob. 23RQCh. 16 - Prob. 24RQCh. 16 - Prob. 25RQCh. 16 - Prob. 26RQCh. 16 - Prob. 27RQCh. 16 - Prob. 28RQCh. 16 - Prob. 29RQCh. 16 - Prob. 30RQCh. 16 - Prob. 31RQCh. 16 - Prob. 1CCCh. 16 - Prob. 2CCCh. 16 - Prob. 3CC
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- Which of the following is the role of axonal Calcium (Ca2+) channels in neuronal communication at the synapse? a) they inhibit the action potential causing it to stop b) Calcium channels have no role in this process c) by allowing calcium to exit the cell, they promote the propagation of action potential across the synapse by creating depolarization d) by blocking calcium entrance, they mediate the contraction of presynaptic axon to facilitate movement e) when they open, calcium enters the presynaptic terminal, promoting fusion of neurotransmitter vesicles with presynaptic membrane, and release of neurotransmitters to the synaptic cleftarrow_forwardPut these events that occur in skeletal muscle in the correct chronological sequence: 1. Activation of voltage-gated dihydropyridine (DHP) receptor in the T-tubule 2. Opening of mechanically-gated ryanodine receptors (RyR) on the sarcoplasmic reticulum 3. Na+ influx through ligand-gated ion channels on the motor end plate 4. Ca2+ binding to troponin 2, 1, 4, 3 4, 3, 2, 1 4, 3, 1, 2 3, 1, 4, 2 3, 1, 2, 4arrow_forwardThe Structure of the acetylcholine receptor is shown below: D. Briefly indicate what the role of the acetylcholine receptor is in an action potential.arrow_forward
- When an action potential from a motor neuron arrives at the neuromuscular junction, a series of events occurs that leads to muscle contraction. Arrange following events in the correct order from first to last.arrow_forward*When dynamic y-motor neurons are activated at the same time as a-motor neurons to muscle, [A] prompt inhibition of discharge in spindle la afferents takes place. [B] clonus is likely to occur. [C] the muscle will not contract. [D] the number of impulses in spindle la afferents is smaller than when a discharge alone is increased. [E] the number of impulses in spindle la afferents is greater than when a discharge alone is increased.arrow_forwardhen an action potential arrives at the nerve terminal of a neuromuscular junction, which of the following statements best describes the events that occur? Depolarisation of the nerve terminal causes the release of ACh which activates nicotinic receptors on the skeletal muscle membrane to cause Ca2+ entry and muscle contraction. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which activates voltage-gated Na+ channels at the end-plate. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores causing the release of ACh which binds to muscarinic receptors at the end plate. Depolarisation of the nerve terminal opens voltage-gated Ca2+ channels, Ca2+ entry brings vesicles containing ACh to the membrane which form fusion pores…arrow_forward
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