Genetics: Analysis and Principles
6th Edition
ISBN: 9781259616020
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16, Problem 12CONQ
Summary Introduction
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The effects of non-
Introduction:
Cell and tissue-specific regulation of expression of genes is important for the proper development of an organism. Some proteins that have been implicated in this regulation are PcG protein complexes and TrxG (Trithorax group) protein complexes.
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Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. Which of the following statements about...Ch. 16.3 - The effects of paramutation may vary with regard...Ch. 16.4 - 1. When mice carrying theallele exhibit a darker...
Ch. 16.4 - 2. If the VIN3 gene had a loss-of-function...Ch. 16.5 - Prob. 1COMQCh. 16.5 - Prob. 2COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 5CONQCh. 16 - Prob. 6CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 8CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 12CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 15CONQCh. 16 - Prob. 16CONQCh. 16 - Explain how the VIN3/PRC2 complex specifically...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - Prob. 6EQCh. 16 - Prob. 7EQCh. 16 - 2. Discuss the similarities and differences of...
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- Outline the three major mechanisms of cell fate determination in developmental genetics. please help me to write 600 word essay.arrow_forwardI am confused about how stem cell transplants works. If you put a semi differentiated tadpole nucleus in a denucleated egg cell, it’ll develop into a fully formed tadpole, but if you put a fully differentiated tadpole nucleus, it won’t (because the genes have already been expressed in a way where the cytoplasmic determinants cannot operate to the fullest). Then how come in stem cell transplants, you use adult nucleuses that are already developed and transplant them into the denucleated egg cells?arrow_forward“In an organism that reproduces asexually, there is no difference between a somatic cell mutation and a germ line mutation.” Is this statement true? Explain.arrow_forward
- In the introduction to this chapter, we discussed the role of famine during early prenatal development and how, through epigenetic effects, it influenced the health of individuals as adults. One effect that has been observed in people who were conceived during the Dutch Hunger Winter is that they suffer more cognitive decline later in life. If these individuals were autopsied after death, what differences might you expect to see in the chromatin of their brain cells? What do the mouse studies of cognition and epigenetic effects suggest?arrow_forwardDiscuss how the anterior portion of the anteroposterior axis is established in Drosophila. What aspects of oogenesis are critical in establishing this axis? What do you think would happen if the bicoid mRNA was not trapped at the anterior end but instead diffused freely throughout the oocyte?arrow_forwardIn Drosophila subobscura, the presence of a recessive gene called grandchildless (gs) causes the offspring of homozygous females, but not those of homozygous males, to be sterile. Can you offer an explanation as to why females and not males are affected by the mutant gene?arrow_forward
- All the cells of one organism share the same genome. However, during development, some cells develop into skin cells while others develop into muscle cells. Briefly explain how the same genetic instructions can result in two different cell types in the same organism.arrow_forwardWhat are non-histone chromosomal proteins?arrow_forwarda) Do the loss of function phenotypes differ between the genes between the genes in figure 1? What does this mean? b) What are the two cell types responsible for producing maternal gene products involved in terminal patterning in the Drosophila cocyte? In which of these two cell types is each of the three genes expressed? c) Based on the phenotypes you observed for the three genes, and on the differences in their expression patterns, which one of the genes do you think is the localised determinant of terminal patterning? d❘ From the gain-of-function experiments, do trunk and torso like work upstream or downstream of torso? Explain. (4 m e) How might you test which of the trunk and torso-like genes acts upstream of the other? f) The torso gene has been shown to have another important role in Drosophila development outside of terminal patterning. What do you think would be a good first experiment to do to begin to investigate possible other roles for the trunk or torso - like genes? C a…arrow_forward
- (a) How does the duplication of individual genes occur? (b) individual that inherit a genetic condition known as xeroderma pigmentosum exhibit an extreme sensitivity to sunlight exposure and often develop skin cancer by the age of 10. What repair pathway is most likely disrupted as a result of such mutation? Explain why?arrow_forwardIn McCune-Albright syndrome, fibrous connective tissue replaces bone, tan patches (café-au-lait spots) dot the skin, and hormone abnormalities cause early puberty and malfunction of the thyroid, pituitary, and adrenal glands. The phenotype is highly variable, and all patients are somatic mosaics for the mutation, which is in the gene GNAS1. Why is the condition seen only in mosaics?arrow_forwardWhite eyes in Drosophila melanogaster result from an X-linked recessive mutation. Occasionally, white-eyed mutants give rise to offspring that possess white eyes with small red spots. The number, distribution, and size of the red spots are variable. Explain how a transposable element could be responsible for this spotting phenomenon.arrow_forward
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