Chapter 16, Problem 3EQ

Summary Introduction

To review:

5-Azacitidineis an inhibitor of DNA methyltransferase and produces an effect upon its introduction into the pregnant mice. The effect on the coat color of the offspring which is carrying A^vy allele.

Introduction:

Epigenetics is defined as astudy ofmechanisms which lead to changes in expression of gene. It is also called epimutation because there is no change in the DNA sequence. However, these changes in the gene expression are passed from one cell to another and are reversible in nature.