Chapter 16, Problem 6CONQ

Summary Introduction

To review:

The effect of the mutation on the expression of Igf2 gene, if the mutation is inherited from the mother and removes the ICR (imprinting control region) next to the Igf2 gene.

Introduction:

The Igf2 is the gene, which is present in mammals, which exhibits epigenetic inheritance. The methylation of DNA (deoxyribonucleic acid)occurs at a specific site called the ICR, which is located between the Igf2 gene and the H19 gene. There is the formation of the loop, which helps in the process of epigenetics and changes the gene expression.