Campbell Biology in Focus (2nd Edition)
2nd Edition
ISBN: 9780321962751
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece
Publisher: PEARSON
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Textbook Question
Chapter 15.4, Problem 2CC
WHAT IF? Study the microarray in Figure 15.17. If a sample from normal tissue is labeled with a green fluorescent dye, and a sample from ca1cerous tissue is labeled red, what color spots would represent genes that you would be interested in if you were studying cancer? Explain.
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Hi, can you elaborate about these two concepts:
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3. Figure on the right shows a DNA
Genes expressed
microarray
assay
of
gene
in cancerous
expression
levels.
In
this
tissue: Red
microarray if a sample with
normal tissue is labeled with
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in normal tissue:
green fluorescent dye, and a
Green
sample with cancerous tissue is
labeled with red, what colored
Genes expressed
in both tissues:
spots would represent genes that
you would be interested in if you
Yellow
were studying cancer? Explain.
Genes expressed
in neither tissue:
Black
GENETICS QUESTION!!
Imagine that you are a geneticist at a hospital and you are given a file for a patient whose family has a history of cancer.
The patient, John Doe, is 18 years old and has had a biopsy done on a tumorous growth in his adrenal gland. He has a sister, Jane, and a brother, Bob, who are younger than he is and who are both healthy. His mother, Betty, has a diagnosis of breast cancer. John’s father, Joe, and John’s paternal grandparents have no history of cancer.
Betty is one of four children. Her brother, Tom, and sister, Lucy, have never had cancer or signs of cancer. Both Tom and Lucy are older than Betty. Betty had another brother, Jake, who died very young of leukaemia. Tom has monozygotic twin daughters who are healthy. Betty’s father, Don, died of soft tissue sarcoma in his thirties. Betty’s mother is alive and healthy. Betty’s paternal grandmother, Don’s mother, died of a brain tumor in her thirties. Don had no siblings.
As part of your research, you also consult…
Chapter 15 Solutions
Campbell Biology in Focus (2nd Edition)
Ch. 15.1 - How does binding of the trp corepressor to its...Ch. 15.1 - Describe the binding of RNA polymerase,...Ch. 15.1 - WHAT IF? A certain mutation in E. coli changes the...Ch. 15.2 - Prob. 1CCCh. 15.2 - Compare the roles of general and specific...Ch. 15.2 - Prob. 3CCCh. 15.3 - WHAT IF? Suppose the mRNA being degraded in Figure...Ch. 15.3 - MAKE CONNECTIONS Inactivation of one of the X...Ch. 15.4 - Describe the role of complementary base pairing...Ch. 15.4 - WHAT IF? Study the microarray in Figure 15.17. If...
Ch. 15 - If a particular operon encodes enzymes for making...Ch. 15 - The functioning of enhancers is an example of A. a...Ch. 15 - Which of the following is an example of...Ch. 15 - Prob. 4TYUCh. 15 - Prob. 5TYUCh. 15 - Which of the following would not be true of cDNA...Ch. 15 - Prob. 7TYUCh. 15 - SCIENTIFIC INQUIRY Imagine you want to study one...Ch. 15 - FOCUS ON EVOLUTION DNA sequences can act as tape...Ch. 15 - FOCUS ON INTERACTIONS In a short essay (100150...Ch. 15 - Prob. 11TYU
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- 1) What are the limitations of targeted versus whole-genome or whole-exome profiling of cancer mutations? 2) What can you infer about mutations that are common to almost all of the cells in a tumor? 3) Summarize the high-level differences between the VCF and MAF file formats. 4) How do germline and somatic mutations differ in terms of their effect on cancer risk and prognosis?arrow_forwardOf the genes in the microarray shown in the lower part of Figure 20.10, are most overexpressed or underexpressed in tumors from patients that remained cancer free for at least five years? Explain your reasoning.arrow_forwardGive detailed Solution with explanation needed....give correct solution. don't use Ai for answering this..arrow_forward
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