BIO 102 General Biology II Updated Edition (Tidewater Community College)
3rd Edition
ISBN: 9781259614064
Author: Tidewater Community College
Publisher: MCG CUSTOM
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Textbook Question
Chapter 15, Problem 8MCQ
Primates share all of the following characteristics EXCEPT
- a. opposable thumbs.
- b. excellent depth perception.
- c. bipedalism.
- d. flat fingernails.
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Digoxin: Intravenous Bolus - Two Compartment Model
Drug
Digoxin
Route:
IV Bolus
Dose:
0.750 mg
Plasma Concentration Time Profile
Beta
Alpha
Time (hrs)
Conc (ng/ml)
LN
(ng/ml)
LN
(ng/ml)
LN
0.00
#NUM!
#NUM!
#NUM!
0.10
12.290
2.509
#NUM!
#NUMI
0.60
6.975
1.942
#NUM!
#NUMI
1.00
4.649
1.537
#NUM!
#NUMI
2.00
2.201
0.789
#NUM!
#NUM!
3.00
1.536
0.429
#NUM!
#NUM!
4.00
1.342
0.294
#NUM!
#NUM!
5.00
1.273
0.241
#NUM!
#NUMI
6.00
1.238
0.213
#NUM!
#NUM!
7.00
1.212
0.192
#NUM!
#NUM!
8.00
1.188
0.172
#NUMI
#NUM!
9.00
1.165
0.153
#NUM!
#NUMI
10.00
1.143
0.134
#NUMI
#NUM!
11.00
1.122
0.115
#NUM!
12.00
1.101
0.096
#NUMI
13.00
1.080
0.077
#NUMI
16.00
1.020
0.020
#NUMI
24.00
0.876
-0.132
#NUMI
Pharmacokinetic Parameters
Parameter
Value
Alpha
B
Beta
Units
ng/ml
hr-1
ng/ml
hr-1
CO
ng/ml
H.C
AUC
ng x hr/ml
Vc
Vbeta
Vss
C
L/hr
TK (alpha)
hr
TX (beta)
days
5+
F3
F4
F5
0+
F6
F7
%
6
95
14
#3
29
&
t
F8
F9
FW
EW
Linuron, a derivative of urea, is used as an herbicide. Linuron serum levels were measured in 4Kg
rabbits following a bolus IV injection of 10mg/kg.
Time (minutes)
Serum Linuron Levels (ug/ml)
following IV dose
10
15.48
20
8.60
30
5.90
45
3.78
60
2.42
90
1.49
120
0.93
180
0.60
240
0.41
300
0.29
360
0.22
Analyze this data and perform the necessary calculations to determine the following pharmacokinetic
parameters from the IV data: (5 points per parameter, 24 parameters/variables ■ 120 points
possible). You do NOT need to submit graphs or data tables.
Give the terminal regression line equation and R or R² value:
Give the x axis (name and units, if any) of the terminal line:
Give the y axis (name and units, if any) of the terminal line:
Give the residual regression line equation and R or R² value:
Give the x axis (name and units, if any) of the residual line:
Give the y axis (name and units, if any) of the residual line:
Chapter 15 Solutions
BIO 102 General Biology II Updated Edition (Tidewater Community College)
Ch. 15.1 - How were conditions on Earth before life began...Ch. 15.1 - Prob. 2MCCh. 15.1 - Prob. 3MCCh. 15.1 - Prob. 4MCCh. 15.2 - How might the endoplasmic reticulum, nuclear...Ch. 15.2 - Prob. 2MCCh. 15.2 - Prob. 3MCCh. 15.3 - Prob. 1MCCh. 15.3 - What types of organisms flourished in the...Ch. 15.3 - How did Palaeozoic life diversify during the...
Ch. 15.3 - Prob. 4MCCh. 15.3 - Prob. 5MCCh. 15.3 - Prob. 6MCCh. 15.4 - Name and describe the three groups of contemporary...Ch. 15.4 - Prob. 2MCCh. 15.4 - Prob. 3MCCh. 15.4 - Prob. 4MCCh. 15.5 - Prob. 1MCCh. 15.5 - Prob. 2MCCh. 15 - Prob. 1MCQCh. 15 - Prob. 2MCQCh. 15 - Photosynthetic cells affected early Earth by a....Ch. 15 - Prob. 4MCQCh. 15 - Prob. 5MCQCh. 15 - Prob. 6MCQCh. 15 - Why was the Mesozoic era extinction significant to...Ch. 15 - Primates share all of the following...Ch. 15 - Prob. 9MCQCh. 15 - DNA evidence suggests that modern humans a. share...Ch. 15 - Explain how the origin of self-replicating...Ch. 15 - Prob. 2WIOCh. 15 - Review the structures of nucleic acids and...Ch. 15 - Prob. 4WIOCh. 15 - The amoeba Pelomyxa palustris is a single-celled...Ch. 15 - Prob. 6WIOCh. 15 - List the major events of the Precambrian supereon...Ch. 15 - Distinguish among the terms primate, hominid,...Ch. 15 - Explain how opposable thumbs, large brains, and...Ch. 15 - Prob. 10WIOCh. 15 - Prob. 11WIOCh. 15 - Use the Internet to learn about National...Ch. 15 - In what ways has culture been an important factor...Ch. 15 - Prob. 14WIOCh. 15 - Compare todays changing culture to biological...Ch. 15 - Prob. 16WIOCh. 15 - Refer to figure 15.31 and the chapter content to...Ch. 15 - Prob. 2PITCh. 15 - Refer to figure 15.31 and the chapter content to...
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