Microbiology: An Introduction
Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 15, Problem 6R
Summary Introduction

To review:

How the Shiga toxin enters a human cell and inhibits protein synthesis.

Concept introduction:

Microorganisms that have the ability to cause infectious diseases are called as pathogens. Illness in an individual is caused either by disturbing the normal metabolic activity of the host or by inducing the host’s immune system to produce a response. Pathogenic bacteria have developed a wide range of mechanisms to infect the human system. Some microbes have the ability to produce toxins, poisonous substance, which contribute to the pathogenicity of the microorganisms. Such pathogens colonize and invade the human system, and ultimately cause serious diseases in human.

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Explain: Healthy Cell Function Overview→ Briefly describe how a healthy cell usually works: metabolism (ATP production), pH balance, glycogen storage, ion transport, enzymes, etc. Gene Mutation and Genetics Part→ Focus on the autosomal recessive mutation and explain: How gene mutation affects the cell. How autosomal inheritance works. Compare the normal and mutated gene sequences simply. → Talk about possible consequences of a faulty hydrolytic enzyme.
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Explain down bellow what happens to the cell: Decreased pH in mitochondria Increased ATP Decreased pH in cytosol Increased hydrolysis Decreasing glycogen and triglycerides Increased MAP kinase activity Poor ion transport → For each one:→ What normally happens?→ What is wrong now?→ How does it mess up the cell?
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