Microbiology: An Introduction
12th Edition
ISBN: 9780321929150
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case
Publisher: PEARSON
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Chapter 15, Problem 5R
Summary Introduction
To review:
The similarities and differences between endotoxins and exotoxins on the following aspects: bacterial source, chemistry, toxicity, and pharmacology.
Introduction:
Microorganisms that have the ability to cause infectious diseases are called as pathogens. Such microorganisms include bacteria,
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What are two reasons microbes will produce toxins?
Selective toxicity of a drug refers to
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to osmotic pressure?
1) drugs that inhibit nucleic acid synthesis
O 2) drugs that inhibit metabolic pathways
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Chapter 15 Solutions
Microbiology: An Introduction
Ch. 15 - Compare pathogenicity with virulence.Ch. 15 - How are capsules and cell wall components related...Ch. 15 - Prob. 3RCh. 15 - Explain how drugs that bind each of the following...Ch. 15 - Prob. 5RCh. 15 - Prob. 6RCh. 15 - Prob. 7RCh. 15 - Which of the following genera is the most...Ch. 15 - How can viruses and protozoa avoid being killed by...Ch. 15 - Prob. 10R
Ch. 15 - The removal of plasmids reduces virulence in which...Ch. 15 - Prob. 2MCQCh. 15 - Prob. 3MCQCh. 15 - All of the following can occur during bacterial...Ch. 15 - The ID50 for Campylobacter sp. is 500 cells; the...Ch. 15 - Prob. 6MCQCh. 15 - A drug that binds to mannose on human cells would...Ch. 15 - The earliest smallpox vaccines were infected...Ch. 15 - Prob. 9MCQCh. 15 - Which of the following statements is true? a. The...Ch. 15 - Prob. 1ACh. 15 - Prob. 3ACh. 15 - How do each of the following strategies contribute...Ch. 15 - On July 8, a woman was given an antibiotic for...Ch. 15 - Explain whether each of the following examples is...Ch. 15 - Cancer patients undergoing chemotherapy are...
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- Compare exotoxin from endotoxin based on the following features FEATURE EXOTOXIN ENDOTOXIN Relation to cell Toxicity Stability Antigenicity Conversion to toxoidarrow_forwardDescribe the four general mechanisms by which microorganisms cause disease.arrow_forwardBelow are a list of virulence factors/ strategies paired with an example of an organism that utilizes them. How do each of the following strategies contribute to the virulence of the pathogen? Strategy - Causes the host to produce more receptors (Organism - Rhinovirus) Strategy - Produces gas as a product of fermentation (Organism - Clostridium perfringens) Strategy - Produces a capsule (organism - Klebsiella pneumonia) Strategy - Ability to move between adjacent cells (organism - Cytomegalovirus) Strategy - Ability to use pilus as a motility structure (organism - Pseudomonas aerogenosa)arrow_forward
- The type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forwardFill in the table:arrow_forwardOur environment contains masses of microorganisms, many of which reside as commensal organisms on our body’s mucosal and epithelial surfaces without causing disease. What two features distinguish a pathogenic microbe from these commensal microbes?arrow_forward
- Describe three different ways in which exotoxins can be transported from a human pathogenic bacterium into a host cellarrow_forwardExplain why antiprotozoal and antihelminthic drugs are likely to be more toxic than antibacterial drugs.arrow_forwardImportant characteristics of antimicrobial drugs include: a) readily delivered to the site of infection b) high toxicity against microbial cells c) do not cause serious side effects in humans d) remains active in body tissues and fluids e) all of the abovearrow_forward
- Select all of the following that applies to the tradeoff between transmission and virulence that applies to many diseases. a) The tradeoff between transmission and virulence means that diseases always evolve to become more virulent. b) If greater virulence limits transmission, that disease will likely evolve to become less virulent than it could be. c) While making more copies of itself can increase the likelihood of transmission occurring, too much replication of the disease can make the host so sick it won't leave the house and spread the disease. d) A strain of a disease that replicates enough to be transmitted, but not so much that the host gets too sick to move, will be favored by natural selection over strains that either make the host too sick or do not replicate enough to be transmitted. e) If a disease can spread without making its host sick (e.g. when the host is asymptomatic), then the tradeoff between transmission and virulence…arrow_forwardPathogenic infections induce damage to the host by a variety of mechanisms. While many mechanisms are direct effects of the pathogen, some damaging mechanisms result from the immune response to the infection. Examples of damage caused by the host immune response are: a) Exotoxin production, endotoxin b) Cell-mediated inmunity, direct cytopathic effect c) Endotoxin, inmmunune complexes d) Direct cythopathic effect, endotoxin e) Cell-mediated inmunity, inmmunune complexesarrow_forwardDiscuss the different types of toxins produced by bacteria.arrow_forward
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