Introduction to General, Organic and Biochemistry
12th Edition
ISBN: 9780357391594
Author: Frederick A. Bettelheim; William H. Brown; Mary K. Campbell
Publisher: Cengage Learning US
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Question
Chapter 15, Problem 47P
Interpretation Introduction
(a)
Interpretation:
Procaine was one of the first local anesthetics. Its hydrochloride salt is marketed as Novocain.
If procaine is chiral or not and if it contains any stereocenter should be identified.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
Interpretation Introduction
(b)
Interpretation:
The nitrogen atom of procaine which is a stronger base should be identified.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
Interpretation Introduction
(c)
Interpretation:
A structural formula for the salt formed by treating procaine with one mole of HCl, showing which nitrogen is protonated and bears the positive charge should be determined.
Concept Introduction:
Procaine contains amino ester group, it is a local anesthetic drug. It is required to relief the pain caused by injection of penicillin. It is also required in dentistry. In some regions, procaine is popular as Novocain.
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LTS
Solid:
AT=Te-Ti
Trial 1
Trial 2
Trial 3
Average
ΔΗ
Mass water, g
24.096
23.976
23.975
Moles of solid, mol
0.01763
001767
0101781
Temp. change, °C
2.9°C
11700
2.0°C
Heat of reaction, J
-292.37J -170.473
-193.26J
AH, kJ/mole
16.58K 9.647 kJ 10.85 kr
16.58K59.64701
KJ
mol
12.35k
Minimum AS,
J/mol K
41.582
mol-k
Remember: q = mCsAT (m = mass of water, Cs=4.184J/g°C) & qsin =-qrxn &
Show your calculations for:
AH in J and then in kJ/mole for Trial 1:
qa (24.0969)(4.1845/g) (-2.9°C)=-292.37J
qsin =
qrxn =
292.35 292.37J
AH in J = 292.375 0.2923kJ
0.01763m01
=1.65×107
AH in kJ/mol =
=
16.58K
0.01763mol
mol
qrx
Minimum AS in J/mol K (Hint: use the average initial temperature of the three trials, con
Kelvin.)
AS=AHIT
(1.65×10(9.64×103) + (1.0
Jimai
For the compound: C8H17NO2
Use the following information to come up with a plausible structure:
8
This compound has "carboxylic acid amide" and ether functional groups.
The peaks at 1.2ppm are two signals that are overlapping one another.
One of the two signals is a doublet that represents 6 hydrogens; the
other signal is a quartet that represents 3 hydrogens.
Vnk the elements or compounds in the table below in decreasing order of their boiling points. That is, choose 1 next to the substance with the highest bolling
point, choose 2 next to the substance with the next highest boiling point, and so on.
substance
C
D
chemical symbol,
chemical formula
or Lewis structure.
CH,-N-CH,
CH,
H
H 10: H
C-C-H
H H H
Cale
H 10:
H-C-C-N-CH,
Bri
CH,
boiling point
(C)
Сен
(C) B
(Choose
Chapter 15 Solutions
Introduction to General, Organic and Biochemistry
Ch. 15.1 - Prob. 15.1QCCh. 15.2 - Problem 16-2 Write a structural formula for each...Ch. 15.2 - Prob. 15.3QCCh. 15.3 - Problem 16-4 Select the stronger base from each...Ch. 15.3 - Prob. 15.5QCCh. 15 - 16-6 Answer true or false. te/7-Butylamine is a 3°...Ch. 15 - Prob. 2PCh. 15 - Prob. 3PCh. 15 - 16-9 In what way are pyridine and pyrimidine...Ch. 15 - Prob. 5P
Ch. 15 - Prob. 6PCh. 15 - Prob. 7PCh. 15 - 16-13 Classify each amino group as primary,...Ch. 15 - Prob. 9PCh. 15 - 16-15 There are eight primary amines with the...Ch. 15 - Prob. 11PCh. 15 - 16-17 Propylamine (bp 48°C), ethylmethylamine (bp...Ch. 15 - 16-18 Account for the fact that 1-butanamine (bp...Ch. 15 - 16-19 2-Me thy 1 propane (bp -12°C), 2-propanol...Ch. 15 - Prob. 15PCh. 15 - Prob. 16PCh. 15 - Prob. 17PCh. 15 - Prob. 18PCh. 15 - Prob. 19PCh. 15 - Prob. 20PCh. 15 - 16-26 The p/fb of amphetamine is approximately 3.2...Ch. 15 - 16-27 Guanidine, p/Ca 13.6, is a very strong base,...Ch. 15 - 16-28 Following is the structural formula of...Ch. 15 - Prob. 24PCh. 15 - Prob. 25PCh. 15 - Prob. 26PCh. 15 - 16*32 Many tumors of the breast are correlated...Ch. 15 - Prob. 28PCh. 15 - Prob. 29PCh. 15 - Prob. 30PCh. 15 - (Chemical Connections 15B ) Identify all...Ch. 15 - Prob. 32PCh. 15 - Prob. 33PCh. 15 - Prob. 34PCh. 15 - Prob. 35PCh. 15 - Prob. 36PCh. 15 - (Chemical Connections 15D ) Suppose you saw this...Ch. 15 - Prob. 38PCh. 15 - Prob. 39PCh. 15 - Prob. 40PCh. 15 - 16-46 Arrange these three compounds in order of...Ch. 15 - Prob. 42PCh. 15 - Prob. 43PCh. 15 - Prob. 44PCh. 15 - Prob. 45PCh. 15 - Prob. 46PCh. 15 - Prob. 47PCh. 15 - Prob. 48PCh. 15 - 16-54 Several poisonous plants, including Atropa...Ch. 15 - Prob. 50PCh. 15 - Prob. 51PCh. 15 - Prob. 52PCh. 15 - 16-58 Following is a structural formula of...Ch. 15 - Prob. 54P
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