FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
5th Edition
ISBN: 9781119750192
Author: Voet
Publisher: WILEY
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Chapter 15, Problem 15E
Summary Introduction
To explain: The advantages of high glycolytic flux for tumor cells.
Concept introduction: Glycolysis is the process of a reaction where conversion of one molecule of glucose to two molecules of pyruvate occurs, such that a sequence of 10 enzyme-catalyzed reactions occurs. In this process, the total production of 2 ATP and the reduction of 2 NAD+ to 2 NADH occurs. Through glycolytic pathway, the flux is adjusted in response to the atmospheric condition of both inside and outside of the cell. The non-equilibrium reactions of glycolysis are the main glycolytic flux control points.
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Chapter 15 Solutions
FUNDAMENTALS OF BIOCHEMISTRY WPNG 1-SEME
Ch. 15 - Prob. 1ECh. 15 - Prob. 2ECh. 15 - 3. The reversible reaction shown here is part of...Ch. 15 - 4. Step 4 of the pentose phosphate pathway...Ch. 15 - 5. The aldolase reaction can proceed in revere as...Ch. 15 - Prob. 6ECh. 15 - 7. Identify the intermediate in the...Ch. 15 - 8. The compound you identified in Problem 7 is a...Ch. 15 - 9. The pyruvate ? lactate reaction in animals is...Ch. 15 - Prob. 10E
Ch. 15 - 11. Why is it possible for the ?G values in Table...Ch. 15 - 12. If a reaction has a ?G0' value of at least...Ch. 15 - 13. Although it is not the primary flux-control...Ch. 15 - 14. What is the advantage of activating pyruvate...Ch. 15 - 15. Tumor cells, which tend to grow rapidly,...Ch. 15 - 16. The pyruvate kinase isozyme in cancerous cells...Ch. 15 - 17. Compare the ATP yield of three glucose...Ch. 15 - 18. If G6P is labeled at its C2 position, where...Ch. 15 - Prob. 19ECh. 15 - Prob. 20ECh. 15 - Prob. 21ECh. 15 - 22. Describe the products of the transketolase...Ch. 15 - Prob. 23CQCh. 15 - 24. The enzyme phosphoglucomutase interconverts...Ch. 15 - 25. You combine 0.2 g of yeast. 0.2 g of sucrose...Ch. 15 - 26. Nerve cells require a source of free energy to...Ch. 15 - Prob. 27CQCh. 15 - Prob. 28CQCh. 15 - 29. Consider the pathway for catabolizing...Ch. 15 - 30. Yeast take up and metabolize galactose, using...Ch. 15 - 31. (a) Describe how glycerol enters the...Ch. 15 - 32. Some organisms can anaerobically convert...Ch. 15 - 33. Explain why some tissues continue to produce...Ch. 15 - 34. Some bacteria catabolize glucose by the...Ch. 15 - Prob. 35CQCh. 15 - 36. For enzymes a–e in Problem 35, identify their...Ch. 15 - Prob. 1MTE
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