The advantages of high glycolytic flux for tumor cells. Concept introduction: Glycolysis is the process of a reaction where conversion of one molecule of glucose to two molecules of pyruvate occurs, such that a sequence of 10 enzyme-catalyzed reactions occurs. In this process, the total production of 2 ATP and the reduction of 2 NAD+ to 2 NADH occurs. Through glycolytic pathway, the flux is adjusted in response to the atmospheric condition of both inside and outside of the cell. The non-equilibrium reactions of glycolysis are the main glycolytic flux control points.

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Chapter 15, Problem 15E

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To explain: The advantages of high glycolytic flux for tumor cells.

Concept introduction: Glycolysis is the process of a reaction where conversion of one molecule of glucose to two molecules of pyruvate occurs, such that a sequence of 10 enzyme-catalyzed reactions occurs. In this process, the total production of 2 ATP and the reduction of 2 NAD+ to 2 NADH occurs. Through glycolytic pathway, the flux is adjusted in response to the atmospheric condition of both inside and outside of the cell. The non-equilibrium reactions of glycolysis are the main glycolytic flux control points.

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