Cardiopulmonary Anatomy & Physiology
Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN: 9781337794909
Author: Des Jardins, Terry.
Publisher: Cengage Learning,
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Chapter 15, Problem 14RQ

Which of the following decreases an individual's stroke volume index?

1. Dobutamine

2. Mechanical ventilation

3. Propranolol

4. Congestive heart failure

A. 2 only

B. 4 only

C. 1 and 3 only

D. 2, 3, and 4 only

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Draw a rough sketch of the control and experimental data using a normal dose/response curve plot: i.e. % of total bound ligand vs. concentration. Indicate Kd and Bmax on this sketch. You don’t need to use exact numbers, but the relative proportions should be close
Name something that could be happening to glutamate transporters that could have this effect on glutamate transport (i.e. the difference in glutamate transporters between control and experimental conditions). (Bonus: if you can also guess what the experimental condition is).
a. For the control condition, calculate Kd. Include units and show your work. b. For the control condition, calculate Bmax. Include units and show your work.  c. For the experimental condition, calculate Kd. Include units and show your work. For the experimental condition, calculate Bmax. Include units and show your work.
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