Cardiopulmonary Anatomy & Physiology
7th Edition
ISBN: 9781337794909
Author: Des Jardins, Terry.
Publisher: Cengage Learning,
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Chapter 15, Problem 12RQ
Summary Introduction
Introduction:
The vascular resistance is observed in the blood flowing through the systemic and the pulmonary vascular system. The resistance to the pulmonary vascular system is lower as compared to the systemic vascular system. The pulmonary vascular resistance reflects the pressure of the right ventricle against which the heart must work to remove blood (afterload) during systole.
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
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E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
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Chapter 15 Solutions
Cardiopulmonary Anatomy & Physiology
Ch. 15 - Prob. 1RQCh. 15 - Prob. 2RQCh. 15 - Prob. 3RQCh. 15 - Prob. 4RQCh. 15 - Prob. 5RQCh. 15 - Prob. 6RQCh. 15 - Prob. 7RQCh. 15 - Prob. 8RQCh. 15 - Prob. 9RQCh. 15 - Prob. 10RQ
Ch. 15 - Prob. 11RQCh. 15 - Prob. 12RQCh. 15 - Prob. 13RQCh. 15 - 14. Which of the following decreases an...Ch. 15 - Prob. 15RQCh. 15 - Prob. 1CAQ1Ch. 15 - Prob. 1CAQ2Ch. 15 - Case 1
3. Why did the patient's PCWP, Cl, SVR, and...Ch. 15 - Case 2
1. Why was a PEEP of 5 cm H2O the "best...Ch. 15 - Prob. 2CAQ2
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