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To determine: The method of development of a transgenic mouse model with a particular neurodegenerative disease.
Introduction: A model organism is an organism which has about 90% genes identical to the humans and on which the studies of human diseases can be conducted. A model organism should be small and have short generation time so that biological studies can be conducted on them conveniently. Drosophila melanogaster and Mus musculus are certain examples of model organisms used to study human diseases.
To determine: The use of model organism to study the disease or look for new treatments.
Introduction: A model organism is an organism which has about 90% genes identical to the humans and on which the studies of human diseases can be conducted. A model organism should be small and have short generation time so that biological studies can be conducted on them conveniently. Drosophila melanogaster and Mus musculus are certain examples of model organisms used to study human diseases.
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Chapter 14 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
- A number of advances have been made in biotechnology. CRISPR/Cas9 one of the most controversial, and has had a lot of media attention in recent years. It is a method by which scientists can precisely edit DNA sequences at exact locations. Benefits obviously include the potential to “repair” mutated genes that cause disease. In fact, preliminary results from one of the earliest clinical trials of CRISPR/Cas9 provide evidence that the technique is safe and feasible to use for treating human diseases. What other potential applications of this application do you see (you can use any organisms to illustrate your answer)? What are the potential dangers or downsides of using this technology? Do you think this technology should be used in gene editing in humans? Explain your stance.arrow_forwardWhat is the advantage of using stem cells for genetherapy or gene editing?arrow_forward-What is DNA cloning? What is the common organism that the scientists use to do cloning (explain briefly how it is done) -What is Gene of Interest? -What are the ethical issues on Biotechnology?arrow_forward
- Please explain in detailarrow_forwardGenetic information has become part of our culture and it is difficult to tell the difference between unmodified and genetically modified food sources such as plant and animals. After reading this module’s material regarding vectors in biotechnology, consider the potential for nanotechnology and scientific advancement.Research nanotechnology and its potential use in biotechnology. In one or two paragraphs, explain the potential advantages and disadvantages of nanotechnology in health care, agriculture, or industry and discuss whether you would or would not support further research.arrow_forwardSite directed mutagenesis is used to: 1.determine the critical base per sequences in a Genome 2. Create genomic libraries 3. Determine the critical amino acids in a protein that allowed to function 4. Amplify dna 5. sequence dnaarrow_forward
- Besides using vector-based methods to transform crop plants, elaborate on THREE (3) other methods to introduce gene of interest into plant cells for the production of transgenic crops.arrow_forwardthis is an example of biotechnology: In order to increase the yield of oil from canola, research focused on ways to reduce competition from competitor weed plants. Weeds can be controlled by spraying with a herbicide that interferes with biological processes, like amino acid anabolic reactions, in the plant cells. A mutant of canola that is resistant to herbicides is sometimes grown in fields that are sprayed with the herbicide. The majority of canola in Canada, though, is genetically modified to be resistant to herbicides. also use the link: https://youtu.be/VS3kcwgIwm0 Question: Evaluating Biotechnologies in Food Systems As we practice being able to describe choices in Biology you will use this consolidation task to organize details about the advantages and disadvantages of biotechnologies. In an ideal world, all solutions to improving our food system would have no negative consequences. But issues in Biology involve the interaction of many different factors and changes in one…arrow_forwardOne concern about using genetically-modified organisms is that many of the methods used to create them introduce into the genome DNA from a different species (i.e. foreign DNA). Which of the following methods has the lowest potential of introducing foreign DNA into the genome?A. A gene knockout in mouse using homologous recombination in ES cellsB. Introduction of a P element vector into the Drosophila germ-lineC. Deletion mutations introduced by CRISPR/Cas9D. Microinjection of a transgene into a mouse pronucleusarrow_forward
- What is, The ethical implications of gene editing in humans. 1. Introduction: a) Begin with a captivating opening that introduces the topic and its significance. b) Clearly state the thesis statement in this case 2. Body: a) Start with the first main point that discusses the potential benefits of gene editing in humans. b) Transition to the second main point which focuses on the ethical concerns and risks associated with gene editing in humans. Discuss issues like equity fairness and the potential for unintended consequences such as harmful side effects or genetic discrimination. c) Present counterarguments to your points. Acknowledge opposing viewpoints but refute with logical reasoning and supporting evidence emphasizing the importance of considering potential long-term consequences and the need for strict ethical guidelines and regulations. 3. Conclusion: a) Summarize your main points and restate your thesis statement emphasizing the ethical implications of gene editing in…arrow_forwardThere is a hypothetical gene related to the nervous system of Drosophila. Describe all the methods, steps, and key substances you need to obtain to use the following techniques in experimental design to study the gene: - In situ hybridization (to find the mRNA) - Immunohistochemistry (to find the protein) - CRISPR-Cas9 (for loss of function) - Expression vector (for gain of function)arrow_forwardThe ability to selectively modify the genome in the mouse has revolutionized mouse genetics. Outline the procedure for generating a knockout mouse at a specific genetic locus. How can the loxP-Cre system be used to conditionally knock out a gene? What is an important medical application of knockout mice?arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Biology (MindTap Course List)BiologyISBN:9781305112100Author:Cecie Starr, Beverly McMillanPublisher:Cengage LearningBiology Today and Tomorrow without Physiology (Mi...BiologyISBN:9781305117396Author:Cecie Starr, Christine Evers, Lisa StarrPublisher:Cengage Learning
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