
Concept explainers
To determine: The method of development of a transgenic mouse model with a particular neurodegenerative disease.
Introduction: A model organism is an organism which has about 90% genes identical to the humans and on which the studies of human diseases can be conducted. A model organism should be small and have short generation time so that biological studies can be conducted on them conveniently. Drosophila melanogaster and Mus musculus are certain examples of model organisms used to study human diseases.
To determine: The use of model organism to study the disease or look for new treatments.
Introduction: A model organism is an organism which has about 90% genes identical to the humans and on which the studies of human diseases can be conducted. A model organism should be small and have short generation time so that biological studies can be conducted on them conveniently. Drosophila melanogaster and Mus musculus are certain examples of model organisms used to study human diseases.

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Chapter 14 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
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- Choose a catecholamine neurotransmitter and describe/draw the components of the synapse important for its signaling including synthesis, packaging into vesicles, receptors, transporters/degradative enzymes. Describe 2 drugs that can act on this system.arrow_forwardThe following figure is from Caterina et al. The capsaicin receptor: a heat activated ion channel in the pain pathway. Nature, 1997. Black boxes indicate capsaicin, white circles indicate resinferatoxin. a) Which has a higher potency? b) Which is has a higher efficacy? c) What is the approximate Kd of capsaicin in uM? (you can round to the nearest power of 10)arrow_forwardWhat is the rate-limiting-step for serotonin synthesis?arrow_forward
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